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[伴有循环抗凝物质的舞蹈病与系统性红斑狼疮。3例]

[Chorea and systemic lupus erythematosus with circulating anticoagulant. 3 cases].

作者信息

Bouchez B, Arnott G, Hatron P Y, Wattel A, Devulder B

出版信息

Rev Neurol (Paris). 1985;141(8-9):571-7.

PMID:4089419
Abstract

Circulating anticoagulant was detected during the course of choreic manifestations in three young women with systemic lupus erythematosus, associated in two cases with false syphilitic serology due to the presence of antiphospholipid antibodies. The high prevalence of the presence of these antibodies in lupic chorea was confirmed by reports of 41 cases in the literature. These findings could suggest a possible pathogenic role for these antibodies in choreic manifestations by either a thrombotic or auto-immune encephalitis mechanism.

摘要

在三名患有系统性红斑狼疮的年轻女性出现舞蹈症表现的过程中检测到循环抗凝物质,其中两例因抗磷脂抗体的存在而伴有假梅毒血清学。文献中41例病例报告证实了这些抗体在狼疮性舞蹈症中的高流行率。这些发现可能提示这些抗体通过血栓形成或自身免疫性脑炎机制在舞蹈症表现中可能具有致病作用。

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