Rumbach L, Caires M C, Warter J M, Collard M, Scheiber C, Gounot D, Dumitresco B, Chambron J
Rev Neurol (Paris). 1985;141(8-9):583-6.
Single or multiple parenchymatous anomalies were detected in 48 of 49 patients with multiple sclerosis by proton magnetic resonance imaging (MRI) combined with a spin-echo sequence in the 4 planes of the section passing through the ventricular bodies. Lesions were identified in the frontal, orbital and particularly juxta-ventricular white substance, and were of variable appearance, the most common being spots in the parenchyma and juxta-ventricular bands. A limited number of sections is sufficient for the MRI study of anomalies in clinically defined multiple sclerosis, the diagnostic value of this examination suggested by these findings requiring confirmation by prospective studies.
通过质子磁共振成像（MRI）结合自旋回波序列，在穿过脑室体的4个层面上，对49例多发性硬化症患者中的48例进行检查，发现了单发或多发的实质异常。病变见于额叶、眶叶，尤其是脑室周围白质，外观各异，最常见的是实质内斑点和脑室周围带。对于临床确诊的多发性硬化症，有限数量的切片足以进行异常情况的MRI研究，这些发现提示该检查的诊断价值有待前瞻性研究加以证实。
