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慢性阻塞性肺疾病患者药物依从性的预测因素:一项横断面研究的证据

Factors Predicting Medication Adherence in Patients with Chronic Obstructive Pulmonary Disease: Evidence from a Cross-Sectional Study.

作者信息

Trinh Le Huyen, Thuy Luu Thi, Hop Nguyen Thi Bich, Oanh Tran Thi Hoang, Thuy Pham Thi

机构信息

Department of Specialized - Community Nursing, Faculty of Nursing, Da Nang University of Medical Technology and Pharmacy, Da Nang, Vietnam.

Department of Practical Nursing, Faculty of Nursing, Duy Tan University, Da Nang, Vietnam.

出版信息

J Caring Sci. 2025 Jun 3;14(2):73-79. doi: 10.34172/jcs.025.33204. eCollection 2025 Jul.

Abstract

INTRODUCTION

Medication adherence is crucial for effective management of chronic obstructive pulmonary disease (COPD). However, the medication adherence rates among patients with COPD is generally low due to various influencing factors. This study aimed to identify predictors of medication adherence among Vietnamese patients with COPD.

METHODS

A cross-sectional study was conducted at a tertiary hospital in Central Vietnam. A total of 104 patients diagnosed with COPD were conveniently recruited between March and June 2022. Data were collected using three structured questionnaires, including demographic and health-related characteristics form, the Beliefs about Medicines Questionnaire, and the General Medication Adherence Scale (GMAS). Descriptive statistics, independent t-test, Chi-square test, univariate logistic regression analysis, and multivariable logistic regression were used for data analysis.

RESULTS

Up to 41.3% of participants adhered to medication. Medication adherence was higher among younger individuals, those with education levels above high school, those with fewer medications, and those who held a stronger positive belief about the necessity of medication.

CONCLUSION

The overall medication adherence rate was moderate. It was significantly influenced by age, educational level, number of medications, and beliefs about the necessity of medication. These findings suggest that healthcare providers should prioritize identifying and supporting patients who are at risk of non-adherence. Moreover, intervention programs should aim to enhance patients' awareness of the necessity of medication in managing COPD.

摘要

引言

药物依从性对于慢性阻塞性肺疾病(COPD)的有效管理至关重要。然而,由于各种影响因素,COPD患者的药物依从率普遍较低。本研究旨在确定越南COPD患者药物依从性的预测因素。

方法

在越南中部的一家三级医院进行了一项横断面研究。2022年3月至6月间,便利抽样招募了104例确诊为COPD的患者。使用三份结构化问卷收集数据,包括人口统计学和健康相关特征表、药物信念问卷和一般药物依从性量表(GMAS)。采用描述性统计、独立样本t检验、卡方检验、单因素逻辑回归分析和多因素逻辑回归进行数据分析。

结果

高达41.3%的参与者坚持服药。年轻人、高中以上学历者、用药较少者以及对药物必要性持有更强积极信念者的药物依从性更高。

结论

总体药物依从率中等。它受到年龄、教育水平、用药数量以及对药物必要性的信念的显著影响。这些发现表明,医疗保健提供者应优先识别和支持有不依从风险的患者。此外,干预项目应旨在提高患者对药物在管理COPD中的必要性的认识。

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