• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

探寻全膝关节置换术的最佳区域镇痛策略:一项关于股三角、收肌管和双缝匠肌下阻滞的双盲随机对照研究(FAD试验)

Pursuing an Optimal Regional Analgesia Strategy for Total Knee Arthroplasty: A Double-Blind Randomized Controlled Study of Femoral Triangle, Adductor Canal, and Dual Subsartorial Blocks (FAD Trial).

作者信息

Sonawane Kartik, Saxena Shlok, Mistry Tuhin, Balavenkatasubramanian Jagannathan, Rajan Soundar, Shanmuganathan Rajasekran

机构信息

Anesthesiology, Ganga Medical Centre and Hospitals, Pvt. Ltd, Coimbatore, IND.

Orthopedics and Joint Replacement, Ganga Medical Centre and Hospitals, Pvt. Ltd, Coimbatore, IND.

出版信息

Cureus. 2025 Aug 27;17(8):e91147. doi: 10.7759/cureus.91147. eCollection 2025 Aug.

DOI:10.7759/cureus.91147
PMID:40895690
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12391534/
Abstract

Background Total knee arthroplasty (TKA) is often associated with intense postoperative pain, which can delay mobilization and hinder recovery. While motor-sparing blocks such as the femoral triangle block (FTB) and adductor canal block (ACB) are commonly used, both offer incomplete analgesic coverage. To overcome these limitations, the dual subsartorial block (DSB) was introduced as a procedure-specific, motor-sparing technique that combines and modifies FTB and ACB into a dual-injection approach for enhanced efficacy. Objective The objective of this study is to compare the analgesic efficacy, motor-sparing effect, opioid-sparing potential, and patient satisfaction among three regional analgesia (RA) techniques, FTB, ACB, and DSB, in patients undergoing TKA. Methods This prospective, double-blind, monocentric trial enrolled 120 patients undergoing unilateral primary TKA, randomized equally into FTB, ACB, or DSB groups (n = 40 each). All patients received standardized spinal anesthesia followed by the assigned ultrasound-guided block. The primary outcome was postoperative quadriceps strength. Secondary outcomes included visual analog scale (VAS) pain scores, rescue opioid use, pain location mapping, patient satisfaction, and block duration. Results Quadriceps strength was preserved in all groups. DSB showed significantly better static and dynamic pain control (p < 0.001), with zero opioid use compared to minimal use in FTB and highest use in ACB. Pain mapping revealed incomplete coverage with ACB, particularly at upper incision sites. DSB provided the longest block duration (>24 hours) and the highest satisfaction scores. Conclusions DSB, which strategically integrates and modifies FTB and ACB, offers superior, comprehensive, and motor-sparing analgesia. Its enhanced anatomical precision and functional benefits suggest that DSB can be considered a reliable, procedure-specific RA technique with a strong potential to improve outcomes in modern TKA care pathways.

摘要

背景

全膝关节置换术(TKA)术后常伴有剧烈疼痛,这可能会延迟活动并阻碍恢复。虽然诸如股三角阻滞(FTB)和收肌管阻滞(ACB)等保留运动功能的阻滞方法常用,但两者的镇痛覆盖范围均不完全。为克服这些局限性,引入了双股薄肌下阻滞(DSB),这是一种针对手术的、保留运动功能的技术,它将FTB和ACB结合并改良为双注射法以提高疗效。

目的

本研究的目的是比较FTB、ACB和DSB这三种区域镇痛(RA)技术在接受TKA的患者中的镇痛效果、保留运动功能的效果、减少阿片类药物使用的潜力以及患者满意度。

方法

这项前瞻性、双盲、单中心试验纳入了120例行单侧初次TKA的患者,将其平均随机分为FTB组、ACB组或DSB组(每组n = 40)。所有患者均接受标准化的脊髓麻醉,随后进行指定的超声引导下阻滞。主要结局是术后股四头肌力量。次要结局包括视觉模拟量表(VAS)疼痛评分、补救性阿片类药物使用、疼痛部位映射、患者满意度和阻滞持续时间。

结果

所有组的股四头肌力量均得以保留。DSB在静态和动态疼痛控制方面表现明显更好(p < 0.001),与FTB组的少量使用和ACB组的大量使用相比,DSB组阿片类药物使用量为零。疼痛部位映射显示ACB的覆盖不完全,尤其是在上部切口部位。DSB的阻滞持续时间最长(> 24小时),满意度评分最高。

结论

DSB通过策略性地整合和改良FTB和ACB,提供了卓越、全面且保留运动功能的镇痛效果。其增强的解剖学精确性和功能优势表明,DSB可被视为一种可靠的、针对手术的RA技术,在现代TKA护理路径中有很大潜力改善治疗结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/890a/12391534/f1f50195337c/cureus-0017-00000091147-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/890a/12391534/2c7f83c5b3ad/cureus-0017-00000091147-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/890a/12391534/e71356494246/cureus-0017-00000091147-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/890a/12391534/ccfe9f1081b2/cureus-0017-00000091147-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/890a/12391534/14352e560a66/cureus-0017-00000091147-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/890a/12391534/4de13f691d6e/cureus-0017-00000091147-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/890a/12391534/91747fd6696b/cureus-0017-00000091147-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/890a/12391534/b81da9ec1b62/cureus-0017-00000091147-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/890a/12391534/f1f50195337c/cureus-0017-00000091147-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/890a/12391534/2c7f83c5b3ad/cureus-0017-00000091147-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/890a/12391534/e71356494246/cureus-0017-00000091147-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/890a/12391534/ccfe9f1081b2/cureus-0017-00000091147-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/890a/12391534/14352e560a66/cureus-0017-00000091147-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/890a/12391534/4de13f691d6e/cureus-0017-00000091147-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/890a/12391534/91747fd6696b/cureus-0017-00000091147-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/890a/12391534/b81da9ec1b62/cureus-0017-00000091147-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/890a/12391534/f1f50195337c/cureus-0017-00000091147-i08.jpg

相似文献

1
Pursuing an Optimal Regional Analgesia Strategy for Total Knee Arthroplasty: A Double-Blind Randomized Controlled Study of Femoral Triangle, Adductor Canal, and Dual Subsartorial Blocks (FAD Trial).探寻全膝关节置换术的最佳区域镇痛策略:一项关于股三角、收肌管和双缝匠肌下阻滞的双盲随机对照研究(FAD试验)
Cureus. 2025 Aug 27;17(8):e91147. doi: 10.7759/cureus.91147. eCollection 2025 Aug.
2
Comparison of Analgesic Effects of Continuous Femoral Nerve Block, Femoral Triangle Block, and Adductor Block After Total Knee Arthroplasty: A Randomized Clinical Trial.全膝关节置换术后连续股神经阻滞、股三角阻滞和收肌管阻滞的镇痛效果比较:一项随机临床试验。
Clin J Pain. 2024 Jun 1;40(6):373-382. doi: 10.1097/AJP.0000000000001211.
3
Prescription of Controlled Substances: Benefits and Risks管制药品的处方:益处与风险
4
Comparative analysis of dual versus single subsartorial block for postoperative analgesia after total knee arthroplasty - A randomized, double-blind study.全膝关节置换术后双股内侧肌下阻滞与单股内侧肌下阻滞用于术后镇痛的比较分析——一项随机双盲研究。
J Anaesthesiol Clin Pharmacol. 2025 Jul-Sep;41(3):470-477. doi: 10.4103/joacp.joacp_206_24. Epub 2025 Jun 2.
5
Is Adductor Canal Block Better Than Femoral Nerve Block in Primary Total Knee Arthroplasty? A GRADE Analysis of the Evidence Through a Systematic Review and Meta-Analysis.在初次全膝关节置换术中,收肌管阻滞比股神经阻滞更好吗?通过系统评价和荟萃分析对证据进行的GRADE分析。
J Arthroplasty. 2017 Oct;32(10):3238-3248.e3. doi: 10.1016/j.arth.2017.05.015. Epub 2017 May 17.
6
Comparison of analgesic efficacy, anti-inflammatory effect, and myotoxicity of ultrasound-guided suprainguinal fascia iliaca block and adductor canal with IPACK combination in patients undergoing total knee arthroplasty under spinal anesthesia: A prospective observational study.脊髓麻醉下全膝关节置换术患者中超声引导下腹股沟上髂筋膜阻滞与内收肌管联合IPACK的镇痛效果、抗炎作用及肌毒性比较:一项前瞻性观察研究
Medicine (Baltimore). 2025 Aug 8;104(32):e43719. doi: 10.1097/MD.0000000000043719.
7
The comparison of adductor canal block with femoral nerve block following total knee arthroplasty: a systematic review with meta-analysis.全膝关节置换术后内收肌管阻滞与股神经阻滞的比较:一项系统评价与荟萃分析
J Anesth. 2016 Oct;30(5):745-54. doi: 10.1007/s00540-016-2194-1. Epub 2016 Jun 4.
8
iPACK block with adductor canal block vs. lumbar erector spinae plane block (L-ESPB) in total knee arthroplasty: a randomized, double-blinded, controlled trial.全膝关节置换术中收肌管阻滞联合iPACK阻滞与腰段竖脊肌平面阻滞(L-ESPB)的比较:一项随机、双盲、对照试验
Anaesthesiol Intensive Ther. 2025 Aug 21;57(1):195-204. doi: 10.5114/ait/208016.
9
Adductor Canal Block Combined with General Analgesia for Patients with Recurrent Patellar Dislocation Undergoing "3-in-1" Procedure Surgery: A Prospective Randomized Controlled Trial.收肌管阻滞联合全身镇痛用于“3-in-1”手术治疗复发性髌骨脱位患者的前瞻性随机对照试验
Orthop Surg. 2023 Jun;15(6):1636-1644. doi: 10.1111/os.13706. Epub 2023 May 16.
10
Analgesic benefits of single-shot versus continuous adductor canal block for total knee arthroplasty: a systemic review and meta-analysis of randomized trials.全膝关节置换术中单次注射与持续股内收肌管阻滞的镇痛效果:一项随机试验的系统评价和荟萃分析
Reg Anesth Pain Med. 2023 Feb;48(2):49-60. doi: 10.1136/rapm-2022-103756. Epub 2022 Nov 8.

本文引用的文献

1
Motor-sparing regional anaesthesia for total knee arthroplasty: a narrative and systematic literature review.全膝关节置换术的保留运动功能区域麻醉:一项叙述性和系统性文献综述
Br J Anaesth. 2025 Feb;134(2):510-522. doi: 10.1016/j.bja.2024.10.041. Epub 2025 Jan 2.
2
Advances in perioperative pain management for total knee arthroplasty: a review of multimodal analgesic approaches.全膝关节置换术围手术期疼痛管理的进展:多模式镇痛方法综述
J Orthop Surg Res. 2024 Dec 19;19(1):843. doi: 10.1186/s13018-024-05324-4.
3
Popliteal plexus block compared with tibial nerve block on rehabilitation goals following total knee arthroplasty: a randomized non-inferiority trial.
腘窝神经丛阻滞与胫骨神经阻滞对全膝关节置换术后康复目标的比较:一项随机非劣效性试验。
Sci Rep. 2024 Oct 11;14(1):23853. doi: 10.1038/s41598-024-74951-y.
4
Nerve Blocks for Post-Surgical Pain Management: A Narrative Review of Current Research.用于术后疼痛管理的神经阻滞:当前研究的叙述性综述
J Pain Res. 2024 Oct 2;17:3217-3239. doi: 10.2147/JPR.S476563. eCollection 2024.
5
Different peripheral nerve blocks for patients undergoing total knee arthroplasty: a network meta-analysis of randomized controlled trials.不同外周神经阻滞用于全膝关节置换术患者:一项随机对照试验的网络荟萃分析。
Arch Orthop Trauma Surg. 2024 Sep;144(9):4179-4206. doi: 10.1007/s00402-024-05507-y. Epub 2024 Oct 7.
6
Application of ultrasound-guided single femoral triangle and adductor canal block in arthroscopic knee surgery: a prospective, double-blind, randomized clinical study.超声引导下单股三角肌和收肌管阻滞在关节镜膝关节手术中的应用:一项前瞻性、双盲、随机临床研究。
BMC Anesthesiol. 2024 May 23;24(1):182. doi: 10.1186/s12871-024-02555-0.
7
Pro and Con: How Important Is the Exact Location of Adductor Canal and Femoral Triangle Blocks?赞成与反对:收肌管和股三角阻滞的精确位置有多重要?
Anesth Analg. 2023 Mar 1;136(3):458-469. doi: 10.1213/ANE.0000000000006234. Epub 2023 Feb 17.
8
Motor-Sparing Effect of Adductor Canal Block for Knee Analgesia: An Updated Review and a Subgroup Analysis of Randomized Controlled Trials Based on a Corrected Classification System.收肌管阻滞用于膝关节镇痛的运动保留效应:基于校正分类系统的随机对照试验的最新综述与亚组分析
Healthcare (Basel). 2023 Jan 10;11(2):210. doi: 10.3390/healthcare11020210.
9
iPACK block (local anesthetic infiltration of the interspace between the popliteal artery and the posterior knee capsule) added to the adductor canal blocks versus the adductor canal blocks in the pain management after total knee arthroplasty: a systematic review and meta-analysis.iPACK 阻滞(即隐动脉和后膝关节囊之间的间隙局部麻醉浸润)联合收肌管阻滞与单纯收肌管阻滞用于全膝关节置换术后疼痛管理的效果比较:一项系统评价和荟萃分析。
J Orthop Surg Res. 2022 Aug 12;17(1):387. doi: 10.1186/s13018-022-03272-5.
10
Combined proximal or distal nerve blocks for postoperative analgesia after total knee arthroplasty: a randomised controlled trial.全膝关节置换术后联合使用近端或远端神经阻滞用于术后镇痛:一项随机对照试验。
Br J Anaesth. 2022 Sep;129(3):427-434. doi: 10.1016/j.bja.2022.05.024. Epub 2022 Jun 28.