• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

肥厚型心肌病患者三度房室传导阻滞的不寻常表现。

An Unusual Presentation of Third-Degree Atrioventricular Block in a Patient With Hypertrophic Cardiomyopathy.

作者信息

Gbee Emmanuel, Ssebuliba Moses Kiwanuka, Nakagaayi Doreen

机构信息

Cardiology, Uganda Heart Institute, Kampala, UGA.

Internal Medicine, John F. Kennedy Medical Center, Monrovia, LBR.

出版信息

Cureus. 2025 Jul 30;17(7):e89041. doi: 10.7759/cureus.89041. eCollection 2025 Jul.

DOI:10.7759/cureus.89041
PMID:40895972
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12396577/
Abstract

Patients with hypertrophic cardiomyopathy (HCM) are commonly affected by ventricular tachyarrhythmias such as ventricular tachycardia, leading to syncope and sudden cardiac death (SCD). Complete atrioventricular (AV) block in patients with HCM is very unusual but may also lead to syncope and SCD. We report a 52-year-old male who presented with recurrent episodes of pre-syncope and effort intolerance. A 12-lead ECG demonstrated deep T-wave inversion in the precordial leads with complete AV dissociation, and a two-dimensional echocardiogram revealed HCM without resting or provoked left ventricular outflow tract obstruction. The patient initially got a temporary transvenous pacemaker, followed by a dual-chamber rate-responsive pacemaker, which was subsequently upgraded to a dual-chamber implantable cardioverter-defibrillator after further risk stratification. Although rare, there have been a few reported cases of HCM complicated by atrioventricular block. This case should alert physicians to the possibility of atrioventricular block in patients with HCM, which could influence the management outcomes.

摘要

肥厚型心肌病（HCM）患者常受室性快速性心律失常影响，如室性心动过速，可导致晕厥和心源性猝死（SCD）。HCM患者出现完全性房室（AV）传导阻滞非常罕见，但也可能导致晕厥和SCD。我们报告一名52岁男性，表现为反复前驱晕厥发作和劳力不耐受。一份12导联心电图显示胸前导联T波深倒置伴完全性房室分离，二维超声心动图显示为HCM，无静息或激发性左心室流出道梗阻。患者最初植入了临时经静脉起搏器，随后植入了双腔频率应答起搏器，在进一步进行危险分层后，该起搏器随后升级为双腔植入式心脏复律除颤器。虽然罕见，但已有少数HCM合并房室传导阻滞的病例报道。该病例应提醒医生注意HCM患者发生房室传导阻滞的可能性，这可能会影响治疗结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fedd/12396577/97f185173200/cureus-0017-00000089041-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fedd/12396577/b544e6bad88e/cureus-0017-00000089041-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fedd/12396577/a884c7f5a99b/cureus-0017-00000089041-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fedd/12396577/ebfe0d5537e1/cureus-0017-00000089041-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fedd/12396577/5861d46c075b/cureus-0017-00000089041-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fedd/12396577/0719fd0fcd83/cureus-0017-00000089041-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fedd/12396577/4af7fb993f3b/cureus-0017-00000089041-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fedd/12396577/1fe4fb3861cd/cureus-0017-00000089041-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fedd/12396577/97f185173200/cureus-0017-00000089041-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fedd/12396577/b544e6bad88e/cureus-0017-00000089041-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fedd/12396577/a884c7f5a99b/cureus-0017-00000089041-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fedd/12396577/ebfe0d5537e1/cureus-0017-00000089041-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fedd/12396577/5861d46c075b/cureus-0017-00000089041-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fedd/12396577/0719fd0fcd83/cureus-0017-00000089041-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fedd/12396577/4af7fb993f3b/cureus-0017-00000089041-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fedd/12396577/1fe4fb3861cd/cureus-0017-00000089041-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fedd/12396577/97f185173200/cureus-0017-00000089041-i08.jpg

相似文献

1
An Unusual Presentation of Third-Degree Atrioventricular Block in a Patient With Hypertrophic Cardiomyopathy.肥厚型心肌病患者三度房室传导阻滞的不寻常表现。
Cureus. 2025 Jul 30;17(7):e89041. doi: 10.7759/cureus.89041. eCollection 2025 Jul.
2
Prescription of Controlled Substances: Benefits and Risks管制药品的处方：益处与风险
3
Sudden cardiac death in childhood RASopathy-associated hypertrophic cardiomyopathy: Validation of the HCM risk-kids model and predictors of events.儿童 RAS 相关肥厚型心肌病中的心源性猝死：HCM 风险儿童模型的验证和事件预测因子。
Int J Cardiol. 2023 Dec 15;393:131405. doi: 10.1016/j.ijcard.2023.131405. Epub 2023 Sep 28.
4
Dual-chamber pacemakers for treating symptomatic bradycardia due to sick sinus syndrome without atrioventricular block: a systematic review and economic evaluation.用于治疗无房室传导阻滞的病态窦房结综合征所致症状性心动过缓的双腔起搏器：一项系统评价与经济学评估
Health Technol Assess. 2015 Aug;19(65):1-210. doi: 10.3310/hta19650.
5
Hypertrophic cardiomyopathy: a systematic review.肥厚型心肌病：一项系统综述。
JAMA. 2002 Mar 13;287(10):1308-20. doi: 10.1001/jama.287.10.1308.
6
Risk factors for sudden cardiac death in childhood hypertrophic cardiomyopathy: A systematic review and meta-analysis.儿童肥厚型心肌病性心原性猝死的危险因素：系统评价和荟萃分析。
Eur J Prev Cardiol. 2017 Jul;24(11):1220-1230. doi: 10.1177/2047487317702519. Epub 2017 May 9.
7
The challenge of risk stratification in hypertrophic cardiomyopathy: Clinical, genetic and imaging insights from a quaternary referral centre.肥厚型心肌病风险分层的挑战：来自四级转诊中心的临床、基因和影像学见解
Int J Cardiol. 2024 Jan 15;395:131416. doi: 10.1016/j.ijcard.2023.131416. Epub 2023 Oct 4.
8
Catecholaminergic Polymorphic Ventricular Tachycardia儿茶酚胺能多形性室性心动过速
9
Validation of Guideline Recommendation on Sudden Cardiac Death Prevention in Hypertrophic Cardiomyopathy.肥厚型心肌病心脏性猝死预防指南推荐的验证
JACC Heart Fail. 2025 Jun;13(6):1014-1026. doi: 10.1016/j.jchf.2024.12.006. Epub 2025 Mar 12.
10
Monomorphic sustained right ventricular outflow tract tachycardia in pregnancy with favorable outcomes: a case report.妊娠合并单形性持续性右心室流出道心动过速且预后良好：一例报告
J Med Case Rep. 2025 Jul 15;19(1):346. doi: 10.1186/s13256-025-05387-9.

本文引用的文献

1
2024 AHA/ACC/AMSSM/HRS/PACES/SCMR Guideline for the Management of Hypertrophic Cardiomyopathy: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines.2024 年美国心脏协会/美国心脏病学会/美国运动医学会/心律学会/起搏与电生理学会/心血管磁共振学会肥厚型心肌病管理指南：美国心脏协会/美国心脏病学会临床实践指南联合委员会的报告。
J Am Coll Cardiol. 2024 Jun 11;83(23):2324-2405. doi: 10.1016/j.jacc.2024.02.014. Epub 2024 May 8.
2
Complete Heart Block in Hypertrophic Cardiomyopathy: A Rare Association.肥厚型心肌病中的完全性心脏传导阻滞：一种罕见的关联。
Kathmandu Univ Med J (KUMJ). 2015 Oct-Dec;13(52):372-4. doi: 10.3126/kumj.v13i4.16841.
3
Clinical Spectrum of PRKAG2 Syndrome.
PRKAG2综合征的临床谱
Circ Arrhythm Electrophysiol. 2016 Jan;9(1):e003121. doi: 10.1161/CIRCEP.115.003121.
4
The emerging role of cardiovascular MRI for risk stratification in hypertrophic cardiomyopathy.心血管 MRI 在肥厚型心肌病危险分层中的新兴作用。
Clin Radiol. 2014 Mar;69(3):221-30. doi: 10.1016/j.crad.2013.11.012. Epub 2014 Jan 10.
5
Recurrent syncope episodes and exercise intolerance in hypertrophic cardiomyopathy combined with atrioventricular conduction disturbance.肥厚型心肌病合并房室传导障碍时的反复晕厥发作和运动不耐受
J Cardiovasc Ultrasound. 2013 Sep;21(3):148-51. doi: 10.4250/jcu.2013.21.3.148. Epub 2013 Sep 30.
6
Cardiomyopathies and myocardial disorders in Africa: present status and the way forward.非洲的心肌病和心肌疾病：现状与未来方向。
Cardiovasc J Afr. 2012 Nov;23(10):552-62. doi: 10.5830/CVJA-2012-046.
7
The anatomical basis of complete atrioventricular block in cats with hypertrophic cardiomyopathy.肥厚型心肌病猫完全性房室传导阻滞的解剖学基础。
J Comp Pathol. 2006 Jul;135(1):25-31. doi: 10.1016/j.jcpa.2006.03.001.
8
Rare association of hypertrophic cardiomyopathy and complete atrioventricular block with prompt disappearance of outflow gradient after DDD pacing.肥厚型心肌病与完全性房室传导阻滞的罕见关联，以及DDD起搏后流出道梯度迅速消失。
Europace. 1999 Oct;1(4):280-2. doi: 10.1053/eupc.1999.0051.
9
Hypertrophic cardiomyopathy presenting with 3rd-degree atrioventricular block.肥厚型心肌病伴三度房室传导阻滞。
Tex Heart Inst J. 1997;24(4):372-5.
10
Idiopathic hypertrophic subaortic stenosis with split His bundle potentials. Electrophysiologic and pathologic correlations.
Circulation. 1980 Dec;62(6):1373-80. doi: 10.1161/01.cir.62.6.1373.