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一名多发性骨髓瘤患者的骨水泥栓塞:病例报告

Cement Embolus in a Patient With Multiple Myeloma: A Case Report.

作者信息

Taylor Zelinda, Lee Sarah, Antil Priya, Singh Didar

机构信息

Internal Medicine, Southern Illinois University School of Medicine, Springfield, USA.

Orthopaedics and Rehabilitation, Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences (PGIMS), Rohtak, IND.

出版信息

Cureus. 2025 Jul 28;17(7):e88940. doi: 10.7759/cureus.88940. eCollection 2025 Jul.

DOI:10.7759/cureus.88940
PMID:40896059
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12391526/
Abstract

Multiple myeloma consists of characteristic symptoms such as hypercalcemia, renal insufficiency, anemia, and bone abnormalities. Kyphoplasty, a minimally invasive surgical intervention, is a commonly used procedure to stabilize bone lesions in patients with multiple myeloma. Despite its relative safety, a potential complication is cement embolism. This can occur if cement leaks into the paravertebral venous system and lodges in distant arteries. It is often asymptomatic and found incidentally on imaging studies. Occasionally, it can also present with dyspnea, chest discomfort, or acute respiratory distress syndrome. This case report highlights a 70-year-old male patient with multiple myeloma who underwent kyphoplasty and developed a pulmonary cement embolism. The treatment options for cement embolism depend on the location, size, and severity of the symptoms, with careful consideration of comorbidities and other potential causes of respiratory distress.

摘要

多发性骨髓瘤具有高钙血症、肾功能不全、贫血和骨异常等特征性症状。椎体成形术是一种微创手术干预手段,是治疗多发性骨髓瘤患者骨病变的常用方法。尽管其相对安全,但潜在并发症是骨水泥栓塞。如果骨水泥漏入椎旁静脉系统并栓塞远处动脉,就可能发生这种情况。它通常无症状,在影像学检查时偶然发现。偶尔,也可能表现为呼吸困难、胸部不适或急性呼吸窘迫综合征。本病例报告重点介绍了一名70岁的多发性骨髓瘤男性患者,他接受了椎体成形术并发生了肺骨水泥栓塞。骨水泥栓塞的治疗方案取决于栓塞的位置、大小和症状严重程度,同时要仔细考虑合并症和其他导致呼吸窘迫的潜在原因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f505/12391526/beae9165cec3/cureus-0017-00000088940-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f505/12391526/beae9165cec3/cureus-0017-00000088940-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f505/12391526/beae9165cec3/cureus-0017-00000088940-i01.jpg

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