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磷化铝所致中毒性心肌炎相关的Brugada波拟表型:一例报告

Brugada Phenocopy Associated With Toxic Myocarditis due to Aluminum Phosphide: A Case Report.

作者信息

Manrique-Marquez Maria V, Juarez-Lloclla Jorge P, Rodríguez-Saldaña Christian A, León-Jiménez Franco

机构信息

Department of Internal Medicine, Peru-Korea Santa Rosa II-2 Hospital, Piura, Peru.

Department of Cardiology, Peru-Korea Santa Rosa II-2 Hospital, Piura, Peru.

出版信息

Case Rep Cardiol. 2025 Aug 22;2025:8858716. doi: 10.1155/cric/8858716. eCollection 2025.

DOI:10.1155/cric/8858716
PMID:40896176
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12396896/
Abstract

We present the case of a 27-year-old woman who ingested aluminum phosphide (AlP) in a suicide attempt, leading to severe toxic myocarditis and a transient Brugada pattern (Brugada phenocopy [BrP]) on her electrocardiogram (ECG). The initial treatment included supportive measures and management of a non-ST elevation acute coronary syndrome. Despite the severity of her condition, the patient stabilized, with normalization of ECG findings and improvement in left ventricular function. This case highlights the importance of recognizing BrP as a potential manifestation of toxic myocarditis, especially in the context of AlP poisoning, and underscores the critical need for early intervention and appropriate management.

摘要

我们报告了一名27岁女性的病例,她因自杀企图摄入了磷化铝(AlP),导致严重的中毒性心肌炎,并在其心电图(ECG)上出现短暂的Brugada波型(Brugada类征[BrP])。初始治疗包括支持性措施和非ST段抬高型急性冠状动脉综合征的管理。尽管病情严重,但患者病情稳定,心电图结果恢复正常,左心室功能改善。该病例强调了认识到BrP作为中毒性心肌炎潜在表现的重要性,尤其是在AlP中毒的情况下,并强调了早期干预和适当管理的迫切需求。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f2c/12396896/d1b21091eacc/CRIC2025-8858716.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f2c/12396896/3548f94c7752/CRIC2025-8858716.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f2c/12396896/d1b21091eacc/CRIC2025-8858716.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f2c/12396896/3548f94c7752/CRIC2025-8858716.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f2c/12396896/d1b21091eacc/CRIC2025-8858716.002.jpg

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本文引用的文献

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Brugada phenocopy vs. Brugada syndrome: Delineating the differences for optimal diagnosis and management.Brugada综合征拟表型与Brugada综合征:明确差异以实现最佳诊断与管理
Curr Probl Cardiol. 2024 Jun;49(6):102566. doi: 10.1016/j.cpcardiol.2024.102566. Epub 2024 Apr 8.
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Expert cardiologists cannot distinguish between Brugada phenocopy and Brugada syndrome electrocardiogram patterns.专业心脏病专家无法区分Brugada综合征拟表型和Brugada综合征的心电图模式。
Europace. 2016 Jul;18(7):1095-100. doi: 10.1093/europace/euv278. Epub 2015 Oct 25.
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J Occup Med Toxicol. 2015 Mar 1;10:10. doi: 10.1186/s12995-015-0050-0. eCollection 2015.
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