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埃塞俄比亚贡德尔农村一名30岁女性,以进行性吞咽困难为表现的食管结核。

Esophageal tuberculosis presenting as progressive dysphagia in a 30-year-old female from rural Gondar, Ethiopia.

作者信息

Mengistu Segenet Bizuneh, Kirub Alula Abebe, Abebe Chalew Mengesha, Abera Samuel Addisu

机构信息

Department of Internal Medicine, School of Medicine, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.

Department of Radiology, School of Medicine, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.

出版信息

IDCases. 2025 Aug 13;41:e02345. doi: 10.1016/j.idcr.2025.e02345. eCollection 2025.

DOI:10.1016/j.idcr.2025.e02345
PMID:40896391
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12390850/
Abstract

Esophageal tuberculosis (TB) is an exceptionally rare manifestation of extra-pulmonary TB, often presenting diagnostic challenges due to its nonspecific symptoms and similarity to malignancies. We report the case of a 30-year-old female from rural Gondar, Ethiopia, who presented with progressive dysphagia and significant weight loss. Diagnosis was confirmed through endoscopic biopsy, revealing tuberculous esophageal ulcer. Our case underscores the importance of considering TB in the differential diagnosis of esophageal ulcers, particularly in TB-endemic regions. In addition, we compare this case with the existing literature, which highlights the varied clinical presentations and diagnostic challenges of esophageal TB.

摘要

食管结核是肺外结核一种极其罕见的表现形式,因其症状不具特异性且与恶性肿瘤相似,常常带来诊断挑战。我们报告了一例来自埃塞俄比亚贡德尔农村地区的30岁女性病例,该患者出现进行性吞咽困难并伴有显著体重减轻。通过内镜活检确诊,显示为结核性食管溃疡。我们的病例强调了在食管溃疡鉴别诊断中考虑结核的重要性,特别是在结核病流行地区。此外,我们将此病例与现有文献进行了比较,这些文献突出了食管结核多样的临床表现和诊断挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f2c/12390850/cbb1a06113c6/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f2c/12390850/39f19be73785/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f2c/12390850/6f4f2fcbbdaf/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f2c/12390850/d66b02c81a4c/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f2c/12390850/237851bc0a82/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f2c/12390850/508fb4e8c1dd/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f2c/12390850/cbb1a06113c6/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f2c/12390850/39f19be73785/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f2c/12390850/6f4f2fcbbdaf/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f2c/12390850/d66b02c81a4c/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f2c/12390850/237851bc0a82/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f2c/12390850/508fb4e8c1dd/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f2c/12390850/cbb1a06113c6/gr6.jpg

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本文引用的文献

1
Role of Endoscopy in Esophageal Tuberculosis: A Narrative Review.内镜检查在食管结核中的作用:一项叙述性综述
J Clin Med. 2022 Nov 27;11(23):7009. doi: 10.3390/jcm11237009.
2
Isolated esophageal tuberculosis: A case report.孤立性食管结核:一例报告。
World J Gastrointest Endosc. 2022 Sep 16;14(9):575-580. doi: 10.4253/wjge.v14.i9.575.
3
Esophageal tuberculosis induced dysphagia: a case report.食管结核所致吞咽困难:一例报告
BMC Gastroenterol. 2022 Mar 22;22(1):131. doi: 10.1186/s12876-022-02211-2.
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Esophageal tuberculosis mimicking submucosal tumor.
Interact Cardiovasc Thorac Surg. 2004 Jun;3(2):274-6. doi: 10.1016/j.icvts.2003.11.016.
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Molecular detection of Mycobacterium tuberculosis: impact on patient care.结核分枝杆菌的分子检测:对患者护理的影响
Clin Chem. 2001 Aug;47(8):1553-8.
6
Molecular diagnosis of mycobacteria.分枝杆菌的分子诊断
Clin Chem. 2001 May;47(5):809-14.