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前列腺黏液腺癌伴极低前列腺特异性抗原水平及复发性疾病:一例报告

Mucinous adenocarcinoma of the prostate with extremely low prostate-specific antigen levels, recurrent disease: a case report.

作者信息

Yu Xu, Yuan Jie, Wang Zhiming, Wang Niannian, He Xiangfei, Liu Jie

机构信息

Linyi People's Hospital, Shandong Second Medical University, Weifang, Shandong, China.

Linyi People's Hospital, Linyi, Shandong, China.

出版信息

Front Oncol. 2025 Aug 14;15:1645306. doi: 10.3389/fonc.2025.1645306. eCollection 2025.

DOI:10.3389/fonc.2025.1645306
PMID:40896436
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12390961/
Abstract

Mucinous adenocarcinoma (MC) is a very rare type of prostate cancer, accounting for less than 1% of prostate adenocarcinomas, and its etiology is still unclear. Its clinical symptoms are similar to those of prostate hyperplasia and follicular carcinoma of the prostate, which are often misdiagnosed, and a definite diagnosis depends on pathological diagnosis, and the secretion of a large amount of mucus is its pathological characteristic. Surgery and endocrine therapy are the main treatment modalities, followed by radiation therapy and comprehensive therapy. Since this disease is rarely reported, in order to improve the understanding and diagnosis of clinically rare MC, we report a case of primary recurrent mucinous adenocarcinoma of the prostate and analyze its clinical features, pathological diagnosis, treatment and prognosis in the light of the literature.

摘要

黏液腺癌(MC)是一种非常罕见的前列腺癌类型,占前列腺腺癌的比例不到1%,其病因仍不清楚。其临床症状与前列腺增生和前列腺滤泡癌相似,常被误诊,明确诊断依赖于病理诊断,大量黏液分泌是其病理特征。手术和内分泌治疗是主要治疗方式,其次是放射治疗和综合治疗。由于该病报道较少,为提高对临床罕见的MC的认识和诊断,我们报告1例原发性复发性前列腺黏液腺癌病例,并结合文献分析其临床特征、病理诊断、治疗及预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac55/12390961/6847c2d80b81/fonc-15-1645306-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac55/12390961/ff5d7cab66e7/fonc-15-1645306-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac55/12390961/e2744e951824/fonc-15-1645306-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac55/12390961/6847c2d80b81/fonc-15-1645306-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac55/12390961/ff5d7cab66e7/fonc-15-1645306-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac55/12390961/e2744e951824/fonc-15-1645306-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac55/12390961/6847c2d80b81/fonc-15-1645306-g003.jpg

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本文引用的文献

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Morphological characteristics of a mucinous adenocarcinoma of the prostate: differential diagnosis considerations.前列腺黏液腺癌的形态学特征:鉴别诊断考量
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Prognosis of mucinous adenocarcinoma of the prostate treated by radical prostatectomy: a study of 47 cases.根治性前列腺切除术治疗前列腺黏液腺癌的预后:47例病例研究
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