Thurnher Dietmar, Simo Ricard, Succo Giovanni, Vilaseca Isabel, Simon Christian
Department of Otorhinolaryngology, Medical University of Graz, Graz, Austria.
Department of Otolaryngology, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
Front Oncol. 2025 Aug 15;15:1520524. doi: 10.3389/fonc.2025.1520524. eCollection 2025.
Total laryngectomy, a surgical procedure involving the complete removal of the larynx, has been a crucial treatment for advanced laryngeal cancer since its introduction in 1873. Over the past 150 years, this procedure has evolved significantly, with improvements in surgical techniques, postoperative care, and rehabilitation methods leading to better survival rates and quality of life for patients. While organ-preserving approaches like radiochemotherapy have gained prominence in recent decades, total laryngectomy remains an essential option for cases of advanced cancer or when other treatments fail. This review explores the history, development, and current role of total laryngectomy in treating laryngeal cancer, as well as comparing it to alternative surgical approaches like open partial laryngectomy and transoral laser microsurgery or organ preservation protocols.
全喉切除术是一种涉及完全切除喉部的外科手术,自1873年引入以来,一直是晚期喉癌的关键治疗方法。在过去的150年里,该手术有了显著发展,手术技术、术后护理和康复方法的改进提高了患者的生存率和生活质量。尽管近几十年来放化疗等器官保留方法备受关注,但全喉切除术对于晚期癌症病例或其他治疗失败的情况仍然是一种重要选择。本综述探讨了全喉切除术在治疗喉癌方面的历史、发展和当前作用,并将其与开放性部分喉切除术、经口激光显微手术等替代手术方法或器官保留方案进行比较。