Bell Michael, Crane Erin, Burks Robert Tucker
Department of Obstetrics and Gynecology, Atrium Health Carolinas Medical Center, Charlotte, North Carolina, United States.
Wake Forest University School of Medicine, Department of Obstetrics and Gynecology, Department of Gynecologic Oncology, Atrium Health Carolinas Medical Center, Levine Cancer Institute, Charlotte, North Carolina, United States.
Gynecol Oncol Rep. 2025 Jun 18;60:101784. doi: 10.1016/j.gore.2025.101784. eCollection 2025 Aug.
Cutaneous horns are rare lesions that consist of a proliferation of keratotic material, often representing animal horns. Rarely, they may be associated with underlying squamous cell carcinomas. Here, we present a case report of a cutaneous horn arising in a squamous cell carcinoma of the vulva.
In this report, we highlight the case of an 84 year-old patient who presented with a vulvar cutaneous horn. After resection, pathology demonstrated an invasive squamous cell carcinoma of the vulva. We provide a review of available literature and describe a rare manifestation of a squamous cell carcinoma of the vulva. Given her frailty, no further treatment was pursued, and she remains in observation without evidence of recurrence.
Our case highlights a rare presentation of a vulvar cutaneous horn arising within invasive squamous cell carcinoma of the vulva. While most cutaneous horns are benign, a subset may harbor malignancy, and therefore excision is warranted. Additional treatment is dependent upon histopathology, disease site, and patient factors.
皮肤角是一种罕见的病变，由角质化物质增生构成，常形似动物角。它们很少与潜在的鳞状细胞癌相关。在此，我们报告一例发生在外阴鳞状细胞癌中的皮肤角病例。
在本报告中，我们重点介绍了一名84岁出现外阴皮肤角的患者。切除术后，病理显示为外阴浸润性鳞状细胞癌。我们回顾了现有文献，并描述了外阴鳞状细胞癌的一种罕见表现。鉴于她身体虚弱，未进行进一步治疗，目前仍在观察中，无复发迹象。
我们的病例突出了在外阴浸润性鳞状细胞癌中出现的外阴皮肤角这一罕见表现。虽然大多数皮肤角是良性的，但一部分可能伴有恶性肿瘤，因此有必要进行切除。进一步的治疗取决于组织病理学、疾病部位和患者因素。
