结直肠癌造口患者的心理弹性和患者激活水平概况：一项潜在类别分析

Profiles of resilience and patient activation among patients with colorectal cancer and an enterostomy: A latent profile analysis.

作者信息

Su Jiayi, Liu Xiaoyu, Deng Xiaolian, Zhang Hua, Li Xia, Yuan Li, Zhou Aixin

机构信息

Department of Nursing, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Gastrointestinal Cancer Center, Chongqing University Cancer Hospital & Chongqing Cancer Institute & Chongqing Cancer Hospital, Chongqing, China.

出版信息

Asia Pac J Oncol Nurs. 2025 Aug 6;12:100768. doi: 10.1016/j.apjon.2025.100768. eCollection 2025 Dec.

DOI:10.1016/j.apjon.2025.100768

PMID:40896755

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12395505/

Abstract

OBJECTIVE

This study aims to identify the latent profiles of resilience among patients with colorectal cancer and an enterostomy, analyze potential influencing factors, and explore the differences in patient activation across different profiles.

METHODS

This cross-sectional study recruited a total of 375 patients with colorectal cancer and an enterostomy from three large public hospitals in Chongqing, China, between August 2024 and January 2025 using convenience sampling. Questionnaires used include sociodemographic information, a 10-item Connor-Davidson Resilience Scale, and a Patient Activation Measure. Latent profile analysis, univariate analysis, and multiple logistic regression analysis were used to explore resilience profiles and identify interindividual variability. Additionally, one-way analysis of variance (ANOVA) and the least significant difference (LSD) method were applied to analyze multiple comparisons between resilience profiles and patient activation.

RESULTS

Following data analyses, the resilience was categorized into three latent profiles: the low resilience-pressure sensitive group (25.8%), moderate resilience-balanced group (38.4%), and high resilience-growth consolidation group (35.8%). Gender, medical insurance types, per capita monthly household income, stoma-related complications, and the duration of stoma establishment were identified as predictors of the participants' latent profiles of resilience. Additionally, significant differences in patient activation levels were observed across the three profiles.

CONCLUSIONS

Resilience in colorectal cancer patients with enterostomy exhibits significant individual variability and is influenced by multiple factors. Health care professionals should focus more on patients with lower resilience and develop targeted, personalized strategies as early as possible. Addressing these differences may offer new insights for improving patient activation.

摘要

目的

本研究旨在识别结直肠癌造口患者的复原力潜在类型，分析潜在影响因素，并探讨不同类型患者在患者激活方面的差异。

方法

本横断面研究于2024年8月至2025年1月期间，采用便利抽样法，从中国重庆的三家大型公立医院招募了375名结直肠癌造口患者。使用的问卷包括社会人口学信息、10项Connor-Davidson复原力量表和患者激活量表。采用潜在类别分析、单因素分析和多因素logistic回归分析来探索复原力类型并识别个体间差异。此外，应用单因素方差分析（ANOVA）和最小显著差异（LSD）法分析不同复原力类型与患者激活之间的多重比较。

结果

数据分析后，复原力被分为三种潜在类型：低复原力-压力敏感组（25.8%）、中等复原力-平衡组（38.4%）和高复原力-成长巩固组（35.8%）。性别、医疗保险类型、家庭月人均收入、造口相关并发症以及造口建立时间被确定为参与者复原力潜在类型的预测因素。此外，在三种类型中观察到患者激活水平存在显著差异。