Adedeji Waheed Adeola, Ishola Adeyinka Ganiyat, Elugbadebo Olufisayo, Oladepo Olayide Muideen, Mudzviti Tinashe, Kaiyo-Utete Malinda, Willis Nicola, Adebayo Dhikrullah Adeyemi, Mtisi Takudzwa Joylyn, Chokuona Kudzai Fortunate Vongai, Ma Qing, Cha Raymond, Hutson Alan, Charurat Man E, Yusuf Oyindamola Bidemi, Maponga Charles, Fehintola Fatai Adewale, Gureje Oye, Morse Gene D
Department of Pharmacology and Therapeutics, University of Ibadan, Ibadan, Nigeria
Department of Clinical Pharmacology, University College Hospital, Ibadan, Nigeria.
BMJ Open. 2025 Sep 2;15(9):e105301. doi: 10.1136/bmjopen-2025-105301.
The mental health of people living with HIV (PLWH) is a growing concern globally, particularly in sub-Saharan Africa (SSA), where there is limited access to mental healthcare, with evidence showing high levels of depression, anxiety and neurocognitive disorders among this population. While Mental Health Disorders (MHDs) can impede HIV care and promote adverse health outcomes, there is limited literature on MHDs among PLWH. This scoping review will explore the existing literature on the burden and factors associated with MHDs among adults living with HIV in SSA.
Arksey and O'Malley's methodological framework will guide the search of this scoping review. Relevant original research articles published in English from 1 January 2000 to 31 May 2025 on MHDs among PLWH in SSA will be identified through searches in the African Index Medicus, African Journal Online, PubMed and Embase databases. Four independent reviewers, working in pairs (one reviewer and one verifier), will screen the titles, abstracts and later the full texts, adopting the population, concept and context framework. Other coauthors will serve as tiebreakers whenever there is disagreement on the eligibility. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews flowchart will be presented. We will perform a narrative synthesis to report our findings.
This scoping review protocol does not require ethical approval, as it relies solely on publicly available existing data and does not involve human participants. We will disseminate the findings from this review through peer-reviewed publications and presentations at local and international conferences.
The protocol was registered in the Open Science Framework (https://osf.io/8ymqu).
全球范围内,感染艾滋病毒者(PLWH)的心理健康问题日益受到关注,尤其是在撒哈拉以南非洲(SSA),那里获得心理保健的机会有限,有证据表明该人群中抑郁症、焦虑症和神经认知障碍的发生率很高。虽然心理健康障碍(MHDs)会妨碍艾滋病毒治疗并导致不良健康后果,但关于PLWH中MHDs的文献有限。本范围综述将探讨关于SSA地区感染艾滋病毒的成年人中MHDs的负担及相关因素的现有文献。
Arksey和O'Malley的方法框架将指导本次范围综述的检索。通过检索《非洲医学索引》、《非洲在线期刊》、PubMed和Embase数据库,将识别出2000年1月1日至2025年5月31日期间以英文发表的关于SSA地区PLWH中MHDs的相关原始研究文章。四名独立评审员将两两合作(一名评审员和一名核实员),采用人群、概念和背景框架筛选标题、摘要,随后筛选全文。每当在资格认定上存在分歧时,其他共同作者将担任裁决者。将呈现系统评价和Meta分析扩展版的范围综述流程图的首选报告项目。我们将进行叙述性综合以报告我们的研究结果。
本范围综述方案无需伦理批准,因为它仅依赖公开可用的现有数据,且不涉及人类参与者。我们将通过同行评审出版物以及在地方和国际会议上的报告来传播本次综述的结果。
该方案已在开放科学框架(https://osf.io/8ymqu)中注册。