毛霉菌病所致面中部缺损的新分类：一项回顾性研究
Midface defects caused by mucormycosis with a new classification: a retrospective study.
作者信息
Fathi Hamid Reza, Arbati Mohammad Mohammadi, Sadrhosseini Seyed Mousa, Molseghi Mohammad Hadi, Davudov Mahammad
机构信息
Department of Plastic, Reconstructive and Aesthetic Surgery, Tehran University of Medical Sciences, Tehran, Iran.
Department of General Surgery, Ayatollah Mousavi Hospital, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
出版信息
Arch Craniofac Surg. 2025 Aug;26(4):147-153. doi: 10.7181/acfs.2025.0002. Epub 2025 Aug 20.
BACKGROUND
The most complex and debated aspect of head and neck reconstructive surgery is the management of midface defects caused by malignant or non-malignant diseases. This study proposes a new classification system for patients with midface defects arising from non-malignant and non-traumatic diseases.
METHODS
In this study, 107 patients with midface defects resulting from mucormycosis were evaluated according to the anatomical locations of involvement and the differences between the affected areas.
RESULTS
Diabetes was identified as the most common underlying disease, while the paranasal sinuses were the most frequently involved sites in cases of mucormycosis. Fourteen patients developed mucormycosis without any associated risk factors, and one patient exhibited brain tissue involvement.
CONCLUSION
To the best of our knowledge, this study is the first to present a comprehensive classification system for patients presenting with midface defects due to mucormycosis.
背景
头颈重建手术中最复杂且争议最大的方面是由恶性或非恶性疾病引起的中面部缺损的处理。本研究针对由非恶性和非创伤性疾病导致中面部缺损的患者提出了一种新的分类系统。
方法
在本研究中，根据受累的解剖位置以及患区之间的差异，对107例因毛霉菌病导致中面部缺损的患者进行了评估。
结果
糖尿病被确定为最常见的基础疾病，而鼻窦是毛霉菌病病例中最常受累的部位。14例患者在无任何相关危险因素的情况下发生了毛霉菌病，1例患者出现脑组织受累。
结论
据我们所知，本研究首次为因毛霉菌病出现中面部缺损的患者提出了一个全面的分类系统。
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