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[《2021年牙髓病学动物研究报告规范清单》中文介绍]

[Chinese introduction to Preferred Reporting Items for Animal Studies in Endodontology 2021 checklist].

作者信息

Cui Xinxin, Pang Xiao, Liu Chang, Pan Jian, Wang Liao, Liu Jiyuan

机构信息

State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.

出版信息

Hua Xi Kou Qiang Yi Xue Za Zhi. 2025 Aug 1;43(4):541-546. doi: 10.7518/hxkq.2025.2025145.

Abstract

Animal experiments are crucial in evaluating the preclinical safety and efficacy of new dental materials, drugs, instruments, and equipment by identifying and eliminating potential health risks to humans. An international team of several dental experts formulated a guideline named Preferred Reporting Items for Animal Studiesin Endodontology (PRIASE) 2021. Consisting of 11 domains, 43 individual items, and a flowchart. PRIASE provides guidance for animal experiments in dentistry and improves the quality of experiment design and reporting. This work introduces the process and basic content of the guideline and interprets the key items of its checklist with specific examples to provide reference for the reporting of animal experiment in dentistry in China.

摘要

动物实验对于评估新型牙科材料、药物、器械和设备的临床前安全性和有效性至关重要,通过识别和消除对人类的潜在健康风险来实现。一个由多位牙科专家组成的国际团队制定了一项名为《2021年牙髓病学动物研究报告规范》(PRIASE)的指南。该指南由11个领域、43个单独项目和一个流程图组成。PRIASE为牙科动物实验提供指导,并提高实验设计和报告的质量。本文介绍了该指南的制定过程和基本内容,并用具体实例解读了其检查表中的关键项目,为我国牙科动物实验报告提供参考。

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The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research.ARRIVE 指南 2.0:报告动物研究的更新指南。
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