Choi Ji Hyeok, Lee Min Young, Jung Jae Yun, Choi Ji Eun
Department of Otorhinolaryngology-Head and Neck Surgery, Dankook University College of Medicine, Dankook University Hospital, Cheonan-si, Republic of Korea.
Eur Arch Otorhinolaryngol. 2025 Sep 3. doi: 10.1007/s00405-025-09661-w.
Acute low-tone sensorineural hearing loss (ALHL) is frequently associated with endolymphatic hydrops. Cervical vestibular-evoked myogenic potentials (cVEMP) have been used to detect saccular hydrops, especially in Meniere's disease, but their role in ALHL is unclear.
To preliminarily investigate whether cVEMP tuning frequency shifts are associated with hearing outcomes in patients with ALHL.
This retrospective study analyzed medical records from 29 patients diagnosed with unilateral ALHL between 2016 and 2021. cVEMP testing utilized 500 Hz and 1000 Hz tone bursts, and frequency tuning shifts were assessed using the 1000/500 Hz amplitude ratio. Hearing recovery and recurrence were evaluated during follow-up.
Of 29 patients, 11 (37.9%) exhibited cVEMP tuning shifts (1000/500 Hz ratio ≥ 0.943). Hearing recovery without recurrence occurred in 55% of patients with tuning shifts versus 72% of patients without shifts; however, this difference was not statistically significant (p > 0.05). Multivariable analysis identified older age as the only significant predictor associated with poorer hearing recovery (B = 0.175, SE = 0.081, p = 0.031, OR = 1.191).
This preliminary study found no statistically significant relationship between cVEMP tuning shifts and hearing outcomes in ALHL. However, patients with tuning shifts appeared to have lower hearing recovery rates, which may warrant further investigation in larger prospective studies.
急性低频感音神经性听力损失（ALHL）常与内淋巴积水相关。颈前庭诱发肌源性电位（cVEMP）已被用于检测球囊积水，尤其是在梅尼埃病中，但它们在ALHL中的作用尚不清楚。
初步研究cVEMP调谐频率变化是否与ALHL患者的听力结果相关。
这项回顾性研究分析了2016年至2021年间29例诊断为单侧ALHL患者的病历。cVEMP测试使用500Hz和1000Hz的短纯音，频率调谐变化通过1000/500Hz振幅比进行评估。在随访期间评估听力恢复和复发情况。
29例患者中，11例（37.9%）出现cVEMP调谐变化（1000/500Hz比值≥0.943）。有调谐变化的患者中55%听力恢复且无复发，无调谐变化的患者中这一比例为72%；然而，这种差异无统计学意义（p>0.05）。多变量分析确定年龄较大是与听力恢复较差相关的唯一显著预测因素（B=0.175，SE=0.081，p=0.031，OR=1.191）。
这项初步研究发现，在ALHL中，cVEMP调谐变化与听力结果之间无统计学意义上的显著关系。然而，有调谐变化的患者听力恢复率似乎较低，这可能值得在更大规模的前瞻性研究中进一步调查。
