Park Myung Jin, Kim Sang Hoon, Kim Sung Su, Yeo Seung Geun
Department of Otorhinolaryngology-Head and Neck Surgery, Kyung Hee University School of Medicine, Seoul, Korea.
Department of Biochemistry and Molecular Biology, Medical Science and Engineering Research Center for Bioreaction to Reactive Oxygen Species, BK-21, Kyung Hee University School of Medicine, Seoul, Korea.
Clin Exp Otorhinolaryngol. 2018 Jun;11(2):96-101. doi: 10.21053/ceo.2017.00948. Epub 2018 Jan 10.
This study analyzed short-term prognosis in patients with acute low frequency hearing loss (ALHL), and also investigate hearing recovery rates in patients with ALHL accompanied vertigo.
Retrospective medical record review of the patients who received treatment for ALHL between June 2005 and June 2015 were analyzed. Of the 84 patients, 53 were without vertigo, and 31 were with vertigo. Of the 31 patients, eight were treated with steroids, seven with diuretics alone, and 16 with both. Clinical and auditory characteristics before and after treatment were compared in these three groups.
Pure tone audiometry after 8 weeks of treatment showed that patients with vertigo had significantly higher than patients without vertigo (=0.020). Patients with vertigo who recovered from ALHL had a greater tendency to receive early treatment than patients who did not recover. Patients who received the two steroid therapy groups (steroids alone and steroids plus diuretics) had a higher recovery rate than patients who received diuretics alone (=0.043 and =0.037, respectively).
The prognosis of patients with ALHL is worse in those with vertigo compared to without vertigo. The hearing recovery rate in patients with vertigo tends to be higher in those treated with steroids than with diuretics alone.
本研究分析急性低频听力损失（ALHL）患者的短期预后，并调查伴有眩晕的ALHL患者的听力恢复率。
对2005年6月至2015年6月期间接受ALHL治疗的患者进行回顾性病历审查分析。84例患者中，53例无眩晕，31例有眩晕。在31例有眩晕的患者中，8例接受了类固醇治疗，7例仅接受利尿剂治疗，16例同时接受两者治疗。比较这三组治疗前后的临床和听觉特征。
治疗8周后的纯音听力测定显示，有眩晕的患者明显高于无眩晕的患者（=0.020）。从ALHL恢复的有眩晕的患者比未恢复的患者有更大的早期治疗倾向。接受两种类固醇治疗组（仅用类固醇和类固醇加利尿剂）的患者比仅接受利尿剂治疗的患者有更高的恢复率（分别为=0.043和=0.037）。
与无眩晕的患者相比，有眩晕的ALHL患者预后更差。有眩晕的患者中，接受类固醇治疗的患者听力恢复率往往高于仅接受利尿剂治疗的患者。
