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索马里一家三级护理医院孕妇疟疾患病率:一项横断面研究。

The Prevalence of Malaria Among Pregnant Women at a Tertiary Care Hospital in Somalia: A Cross-Sectional Study.

作者信息

Mohamud Said Mohamed, Doğan Serpil, Hussein Ahmed Issak, Mohamud Rahma Yusuf Haji, Orhan Zerife, Doğaner Adem

机构信息

Department of Medical Microbiology, Mogadishu Somalia Turkiye Recep Tayyip Erdogan Training and Research Hospital, Medical Microbiology Laboratory, Mogadishu, Somalia.

Department of Obstetrics and Gynecology, Mogadishu Somalia Turkiye Recep Tayyip Erdogan Training and Research Hospital, Medical Microbiology Laboratory, Mogadishu, Somalia.

出版信息

Biomed Res Int. 2025 Aug 24;2025:6730167. doi: 10.1155/bmri/6730167. eCollection 2025.

Abstract

In countries like Somalia, where health infrastructure is inadequate and malaria is endemic, immunosuppression during pregnancy increases the risk of placental malaria; this, in turn, leads to anemia, low birth weight, preterm delivery, and stillbirth, causing severe complications that pose a life-threatening risk to both the mother and fetus. The aim of this study was to investigate the prevalence and associated factors of malaria parasitemia among pregnant women attending the obstetric clinic of a tertiary hospital in Somalia. This cross-sectional study, conducted from November 2022 to January 2023 at a tertiary hospital in Mogadishu, involved 398 pregnant women. Both symptomatic and asymptomatic participants were screened for malaria using Giemsa-stained blood smear microscopy. Associations between variables and malaria prevalence were analyzed using IBM SPSS 22 with chi-square tests and logistic regression. Among 398 pregnant women, 238 (59.8%) tested positive for malaria. Of the 238 malaria cases, 218 (91.6%) were revealed as cases. Being in the second trimester (OR: 0.524, 95% CI: 0.279-0.983; = 0.044), third trimester (OR: 0.442, 95% CI: 0.245-0.797; = 0.007), and indoor residual spraying (IRS) (OR: 0.192, 95% CI: 0.108-0.342; < 0.001) were significantly associated with decreased odds of malaria in pregnancy. The study revealed a high prevalence of malaria in pregnancy, predominantly caused by . Targeted education campaigns focusing on women in the second trimester and those not using preventive measures such as IRS or ITNs should be prioritized, along with routine malaria screening at every antenatal care visit.

摘要

在索马里这样卫生基础设施不足且疟疾为地方病的国家,孕期免疫抑制会增加胎盘疟疾的风险;这进而会导致贫血、低出生体重、早产和死产,引发严重并发症,对母亲和胎儿都构成危及生命的风险。本研究的目的是调查在索马里一家三级医院产科门诊就诊的孕妇中疟疾寄生虫血症的患病率及相关因素。这项横断面研究于2022年11月至2023年1月在摩加迪沙的一家三级医院开展,涉及398名孕妇。有症状和无症状参与者均通过吉姆萨染色血涂片显微镜检查筛查疟疾。使用IBM SPSS 22通过卡方检验和逻辑回归分析变量与疟疾患病率之间的关联。在398名孕妇中,238名(59.8%)疟疾检测呈阳性。在这238例疟疾病例中,218例(91.6%)被确诊为病例。处于孕中期(比值比:0.524,95%置信区间:0.279 - 0.983;P = 0.044)、孕晚期(比值比:0.442,95%置信区间:0.245 - 0.797;P = 0.007)以及室内滞留喷洒(IRS)(比值比:0.192,95%置信区间:0.108 - 0.342;P < 0.001)与孕期疟疾患病几率降低显著相关。该研究揭示了孕期疟疾的高患病率,主要由……引起。应优先开展针对孕中期女性以及未采取IRS或长效驱虫蚊帐等预防措施的女性的针对性教育活动,同时在每次产前检查时进行常规疟疾筛查。

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