Zhan Zongyuan, Zhu Yuandong, Pan Wanneng, Zhang Xiantu, Hou Qinming, Wu Bo
Department of Gastroenterology, Xixi Hospital, Hangzhou, Zhejiang 310023, P.R. China.
Department of Surgery, Xixi Hospital, Hangzhou, Zhejiang 310023, P.R. China.
Exp Ther Med. 2025 Aug 19;30(4):202. doi: 10.3892/etm.2025.12952. eCollection 2025 Oct.
Hepatic mucinous cystic neoplasms (MCN) are rare cystic tumors that are predominantly observed in females, with a low incidence rate in males. To date, few cases of aggressive MCN have been reported in male patients. The current study reports the case of a 74-year-old male patient who presented to Xixi Hospital with abdominal distension. Results of imaging investigations revealed a cystic lesion in the liver and histopathological examination demonstrated positive staining for caudal type homeobox 2, cytokeratin 20, postmeiotic segregation increased 2, progesterone receptor and α-inhibin, leading to a definitive diagnosis of hepatic mucinous cystadenoma. Collectively, the results of the present article demonstrated that hepatic MCN should be considered in the differential diagnosis of cystic liver lesions, including in male patients. A comprehensive evaluation that integrates clinical characteristics, and imaging and histopathological findings is essential for the optimal management of this condition.
肝脏黏液性囊性肿瘤(MCN)是一种罕见的囊性肿瘤,主要见于女性,男性发病率较低。迄今为止,男性患者中侵袭性MCN的病例报道较少。本研究报告了一名74岁男性患者的病例,该患者因腹胀就诊于西溪医院。影像学检查结果显示肝脏有一个囊性病变,组织病理学检查显示尾型同源盒2、细胞角蛋白20、减数分裂后分离增加2、孕激素受体和α-抑制素染色呈阳性,最终确诊为肝脏黏液性囊腺瘤。总体而言,本文结果表明,在包括男性患者在内的肝脏囊性病变鉴别诊断中应考虑肝脏MCN。综合评估临床特征、影像学和组织病理学检查结果对于该病的最佳治疗至关重要。