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间歇性禁食在2型糖尿病治疗中的应用

Intermittent fasting in the treatment of type 2 diabetes.

作者信息

Dyńka Damian, Rodzeń Łukasz, Rodzeń Mateusz, Łojko Dorota, Deptuła Adam, Grzywacz Żaneta, Kraszewski Sebastian, Bartoń Karolina, Martin Peter, Deptuła Anna Małgorzata, Berry Ken, Unwin David

机构信息

Institute of Health Sciences, Faculty of Medical and Health Sciences, University of Siedlce, Siedlce, Poland.

Rodzen Brothers Foundation, Wieleń, Poland.

出版信息

Front Nutr. 2025 Aug 18;12:1629154. doi: 10.3389/fnut.2025.1629154. eCollection 2025.

Abstract

The increasing prevalence of type 2 diabetes mellitus (T2DM) has inspired researchers to investigate therapies and tools supporting the treatment of this disease. One such tool is intermittent fasting (IF). Given the nature and mechanism of action of IF, it would be logical for it to have a beneficial effect on T2DM patients. This study analyzes the role of IF in the treatment of type 2 diabetes, used alongside standard recommendations, based on the current literature available to the authors. The authors discuss the benefits of IF in T2DM treatment, such as improved glycaemic control, improved insulin sensitivity, facilitated adherence to recommendations, weight reduction, and lower risk of complications. This study covers the results of meta-analyses, systematic reviews, and randomized controlled trials (RCTs) and shows how novel technologies, including continuous glucose monitors and mobile applications, can support the implementation of IF. The importance of safety monitoring is also highlighted, particularly in insulin-treated patients due to the potential risk of hypoglycaemia.

摘要

2型糖尿病(T2DM)患病率的不断上升促使研究人员探索支持该疾病治疗的疗法和工具。间歇性禁食(IF)就是这样一种工具。鉴于IF的性质和作用机制,它对T2DM患者产生有益影响是合乎逻辑的。本研究基于作者可获取的当前文献,分析了IF在与标准建议一起使用时对2型糖尿病治疗的作用。作者讨论了IF在T2DM治疗中的益处,如改善血糖控制、提高胰岛素敏感性、促进对建议的依从性、减轻体重以及降低并发症风险。本研究涵盖了荟萃分析、系统评价和随机对照试验(RCT)的结果,并展示了包括连续血糖监测仪和移动应用程序在内的新技术如何支持IF的实施。还强调了安全监测的重要性,特别是在接受胰岛素治疗的患者中,因为存在低血糖的潜在风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b112/12400867/62542bdd7a1c/fnut-12-1629154-g001.jpg

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