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皮肤孢子丝菌病现状更新:一篇叙述性综述

Updates on Current Situation of Cutaneous Sporotrichosis: A Narrative Review.

作者信息

Shi Jing, Zhang Wei, Liu Xiao, Li Mingcheng

机构信息

Department of Dermatology, Jilin Central Hospital, Jilin, 132011, People's Republic of China.

Department of Clinical Laboratory, Jilin Central Hospital, Jilin, 132011, People's Republic of China.

出版信息

Int J Gen Med. 2025 Aug 27;18:4863-4871. doi: 10.2147/IJGM.S531445. eCollection 2025.

DOI:10.2147/IJGM.S531445
PMID:40901371
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12399893/
Abstract

Sporotrichosis, a cutaneous or subcutaneous infection caused by the dimorphic fungus Sporothrix species, is widely distributed in China, with a notably higher incidence during colder seasons in northeastern Jilin Province. Recent advancements in taxonomy have significantly improved our understanding of diagnosis, epidemiology, and treatment strategies. In this review, we described the updated overview of recent progress of sporotrichosis, including etiology, epidemiology, clinical manifestations, diagnostic approaches, and treatment strategies, to provide a comprehensive description of preventive measures and control strategies aimed at facilitating future breakthroughs in research. We highlighted the geographical and population distributions specific to Jilin, China. The ongoing research efforts of novel diagnostic technologies, nanodrugs or nanoformulations treatment options are developed to advance knowledge about this sporotrichosis and its agents.

摘要

孢子丝菌病是由双相真菌孢子丝菌属引起的皮肤或皮下感染,在中国广泛分布,在吉林省东北部寒冷季节发病率显著更高。分类学的最新进展显著提高了我们对诊断、流行病学和治疗策略的认识。在本综述中,我们描述了孢子丝菌病的最新进展概述,包括病因、流行病学、临床表现、诊断方法和治疗策略,以全面描述旨在促进未来研究突破的预防措施和控制策略。我们强调了中国吉林特有的地理和人群分布。正在开展新型诊断技术、纳米药物或纳米制剂治疗方案的研究工作,以增进对这种孢子丝菌病及其病原体的了解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5c3/12399893/b74e4c544999/IJGM-18-4863-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5c3/12399893/43dab5b0d263/IJGM-18-4863-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5c3/12399893/6feccf7fe58d/IJGM-18-4863-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5c3/12399893/b74e4c544999/IJGM-18-4863-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5c3/12399893/43dab5b0d263/IJGM-18-4863-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5c3/12399893/6feccf7fe58d/IJGM-18-4863-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5c3/12399893/b74e4c544999/IJGM-18-4863-g0003.jpg

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本文引用的文献

1
Current situation of sporotrichosis in China.中国的孢子丝菌病现状。
Future Microbiol. 2024 Aug 12;19(12):1097-1106. doi: 10.1080/17460913.2024.2352283. Epub 2024 Jul 26.
2
Sporotrichosis: Using scanning electron microscopy to decipher the "blackish-red dot sign" observed under dermoscopy.孢子丝菌病:利用扫描电子显微镜解读皮肤镜下观察到的“黑红色点状征”
Skin Res Technol. 2024 Jun;30(6):e13775. doi: 10.1111/srt.13775.
3
Misdiagnosis of cutaneous facial sporotrichosis: An analysis of five cases.误诊的皮肤面部孢子丝菌病:五例分析。
J Cosmet Dermatol. 2024 Sep;23(9):3000-3004. doi: 10.1111/jocd.16335. Epub 2024 Apr 23.
4
Dermoscopy of Fixed Cutaneous Sporotrichosis With a Follow-Up Till Cure: A Case Report.固定型皮肤孢子丝菌病的皮肤镜检查及随访至治愈:一例报告
Cureus. 2024 Mar 11;16(3):e55960. doi: 10.7759/cureus.55960. eCollection 2024 Mar.
5
Low toxicity contributes to Sporothrix globosa invade the skin of patients in low-epidemic areas of China.低毒性有助于 S. globosa 入侵中国低流行地区患者的皮肤。
Mycoses. 2024 Apr;67(4):e13724. doi: 10.1111/myc.13724.
6
Sporotrichoid Primary Cutaneous Nocardiosis: A Rare Case of Isolated Upper-Limb Involvement in a Housewife.孢子丝菌病样原发性皮肤诺卡菌病:一名家庭主妇仅上肢受累的罕见病例。
Indian Dermatol Online J. 2023 Oct 5;15(2):270-273. doi: 10.4103/idoj.idoj_133_23. eCollection 2024 Mar-Apr.
7
Emergence of zoonotic sporotrichosis in Brazil: a genomic epidemiology study.巴西动物源孢子丝菌病的出现:一项基因组流行病学研究。
Lancet Microbe. 2024 Mar;5(3):e282-e290. doi: 10.1016/S2666-5247(23)00364-6. Epub 2024 Feb 29.
8
A Randomized Clinical Trial Comparing Itraconazole and a Combination Therapy with Itraconazole and Potassium Iodide for the Treatment of Feline Sporotrichosis.一项比较伊曲康唑以及伊曲康唑与碘化钾联合疗法治疗猫孢子丝菌病的随机临床试验。
J Fungi (Basel). 2024 Jan 26;10(2):101. doi: 10.3390/jof10020101.
9
A case of chronic wounds caused by infection was rapidly detected by metagenomic next generation sequencing.通过宏基因组二代测序快速检测出一例由感染引起的慢性伤口病例。
Heliyon. 2024 Jan 10;10(2):e24420. doi: 10.1016/j.heliyon.2024.e24420. eCollection 2024 Jan 30.
10
Cutaneous disseminated sporotrichosis in an immunocompetent farmer.一名免疫功能正常的农民发生皮肤播散性孢子丝菌病。
Med Mycol Case Rep. 2024 Jan 5;43:100626. doi: 10.1016/j.mmcr.2023.100626. eCollection 2024 Mar.