de Andrade Galliano Daros Bastos Fernanda, de Farias Marconi Rodrigues, Gremião Isabella Dib Ferreira, Bridi Cavassin Francelise, Dos Santos Monti Fabiana, Vilas Boas Rogério Rodrigues, Lustosa Bruno Paulo Rodrigues, Razzolini Emanuel, Vicente Vânia Aparecida, Queiroz-Telles Flávio
Universidade Federal do Paraná, Curitiba, 80000-000, Brazil.
Pontifícia Universidade Católica do Paraná, Curitiba, 80000-000, Brazil.
Med Mycol. 2025 Jun 5;63(6). doi: 10.1093/mmy/myaf051.
Cat-transmitted sporotrichosis (CTS) by Sporothrix brasiliensis is an important epizoonosis with alarming numbers of cases involving felines, canines, and humans. Considering the increasing incidence of CTS this study sought to elucidate the epidemiological characteristics of cats with sporotrichosis and evaluate the potential transmission routes of S. brasiliensis in several biological samples from cats with sporotrichosis. Samples were collected from ulcerated skin lesions, front paws, nasal cavity, and droplets collected from sick cats during sneezing episodes in a veterinarian university hospital, in the city of Curitiba, southern Brazil, between June 2021 and April 2022. A total of 100 cats with sporotrichosis were enrolled in the study. The fungus was isolated in 60% of samples from the nasal cavity and 71% of respiratory droplets. The growth of S. brasiliensis on the right and left front paw was observed in 41% of the cats included, and in 38%, there was growth of the fungus even without an apparent lesion on the paw. Of the infected cats, 64% had multifocal lesions throughout the body. The identification of S. brasiliensis in samples of exudate, paws, nasal cavity, and sneeze droplets suggests that transmission can occur not only through classic routes, but also through the movement of the infected cat, as well as through respiratory droplets expelled by the cat sneezing or nasal drip. Furthermore, the presence of S. brasiliensis on the paws of sick cats indicates the possibility that the fungus is being disseminated in the environment in which the animal lives.
由巴西孢子丝菌引起的猫传播孢子丝菌病（CTS）是一种重要的动物传染病，涉及猫、犬和人类的病例数量惊人。鉴于CTS发病率不断上升，本研究旨在阐明患有孢子丝菌病的猫的流行病学特征，并评估巴西孢子丝菌在患有孢子丝菌病的猫的几种生物样本中的潜在传播途径。2021年6月至2022年4月期间，在巴西南部库里蒂巴市的一所兽医大学医院，从患有孢子丝菌病的猫的溃疡皮肤病变、前爪、鼻腔以及打喷嚏时收集的飞沫中采集样本。共有100只患有孢子丝菌病的猫参与了这项研究。在60%的鼻腔样本和71%的呼吸道飞沫中分离出了真菌。在所纳入的猫中，41%的猫的左右前爪上观察到了巴西孢子丝菌的生长，38%的猫即使爪子上没有明显病变也有真菌生长。在受感染的猫中，64%全身有多灶性病变。在渗出液、爪子、鼻腔和喷嚏飞沫样本中鉴定出巴西孢子丝菌，这表明传播不仅可以通过经典途径发生，还可以通过受感染猫的活动以及猫打喷嚏或鼻滴排出的呼吸道飞沫发生。此外，患病猫爪子上存在巴西孢子丝菌表明真菌有可能在动物生活的环境中传播。
