Jeon Yeong, Kim Kyoung Yun, Yun Jung-Mi
Department of Food and Nutrition, Chonnam National University, Gwangju 61186, Korea.
Prev Nutr Food Sci. 2025 Aug 31;30(4):295-304. doi: 10.3746/pnf.2025.30.4.295.
The Framingham risk score (FRS) is used to assess an individual's risk of developing coronary heart disease (CHD) within 10 years by evaluating CHD risk factors. Despite the increasing mortality rate from CHD, there are limited studies examining the association between the atherogenic coefficient (AC), atherogenic index of plasma (AIP), dietary intake (assessed using a food frequency questionnaire), and FRS-CHD in Korea. The FRS is based on the following coronary risk factors: age, sex, total cholesterol, high-density lipoprotein cholesterol, smoking habits, and systolic blood pressure. The present study aimed to examine the factors that increase the risk of developing CHD in middle-aged men using the FRS based on the 2014-2015 Korea National Health and Nutrition Examination Survey (KNHANES). Data from 1,478 middle-aged men who participated in the 2014-2015 KNHANES were used. As the AC [odds ratio (OR), 6.06; 95% confidence interval (CI), 4.38-8.38; <0.001] and AIP (OR, 3.93; 95% CI, 1.93-8.01; <0.001) increased by 1 unit, the risk of developing CHD was significantly higher in the high-risk group than in the low-risk group after adjusting for potential confounding factors. In the high-risk group, the CHD risk decreased with an increase in egg intake per serving (OR, 0.84; 95% CI, 0.75-0.94; <0.01). The AC, AIP, and egg intake were potent determinants of the high-risk group compared with the low-risk group. Blood cholesterol levels and diet control can decrease the CHD risk in the next 10 years.
弗雷明汉风险评分(FRS)通过评估冠心病(CHD)风险因素来评估个体在10年内患冠心病的风险。尽管冠心病死亡率不断上升,但在韩国,关于致动脉粥样硬化系数(AC)、血浆致动脉粥样硬化指数(AIP)、饮食摄入(使用食物频率问卷评估)与FRS-CHD之间关联的研究有限。FRS基于以下冠心病风险因素:年龄、性别、总胆固醇、高密度脂蛋白胆固醇、吸烟习惯和收缩压。本研究旨在利用基于2014 - 2015年韩国国家健康与营养检查调查(KNHANES)的FRS,研究中年男性患冠心病风险增加的因素。使用了参与2014 - 2015年KNHANES的1478名中年男性的数据。在校正潜在混杂因素后,随着AC [比值比(OR),6.06;95%置信区间(CI),4.38 - 8.38;<0.001]和AIP(OR,3.93;95% CI,1.93 - 8.01;<0.001)每增加1个单位,高危组患冠心病的风险显著高于低危组。在高危组中,每份鸡蛋摄入量增加,冠心病风险降低(OR,0.84;95% CI,0.75 - 0.94;<0.01)。与低危组相比,AC、AIP和鸡蛋摄入量是高危组的有力决定因素。血液胆固醇水平和饮食控制可降低未来10年患冠心病的风险。