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[从血浆和组织提取物中分离纤维蛋白组装抑制剂]

[Isolation of fibrin assembly inhibitor from plasma and tissue extracts].

作者信息

Byshevskiĭ A Sh, Chiriat'ev E A, Umutbaeva M K

出版信息

Vopr Med Khim. 1985 Sep-Oct;31(5):30-2.

PMID:4090362
Abstract

Procedures for isolation of an inhibitor of the fibrin self association are described. The procedures involved dialysis across cuprophane or cellophane T-100, ion exchange chromatography (the first method) or gel filtration (the second method). The product containing amino acid impurities was obtained after dialysis across cuprophane and ion exchange chromatography; a homogeneous inhibitor was isolated by means of dialysis across cellophane T-100 and gel filtration through Sephadex G-50.

摘要

描述了分离纤维蛋白自缔合抑制剂的方法。这些方法包括通过铜氨丝或T - 100玻璃纸进行透析、离子交换色谱法(第一种方法)或凝胶过滤法(第二种方法)。经铜氨丝透析和离子交换色谱法后得到含有氨基酸杂质的产物;通过T - 100玻璃纸透析和Sephadex G - 50凝胶过滤分离出一种纯的抑制剂。

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