[The role of non-collagenous proteins in the mineralization of distraction bone regenerates].

Mature solid bone of dogs before an after substitution of diaphyseal defect using monolocal distraction osteosynthesis by Ilizarov as well as the growth zone and the ossified fragments of the regenerate produced were studied. In reparative osteogenesis proteoglycans and sialoproteins participated sequently in the management of calcification, as shown by analysis of specific correlations between mineral (calcium, phosphorus, carbonate and citrate) and organic components (collagen, non-collagenous proteins, hexuronic and sialic acids) in demineralized bone as well as in zones of the primary mineral deposition and crystallization, Solubilization of the complex of non-collagenous proteins and calcium phosphate might be important in demineralization of intact bone tissue of the animals studied.