Rao H Murali, Krishnan Rajkumar, Shivalingam Chitra, Ramadoss Ramya
Conservative Dentistry and Endodontics, DA Pandu Memorial RV Dental College, Bengaluru, India.
Department of Oral Pathology, SRM Dental College, Chennai, India.
Restor Dent Endod. 2025 Aug;50(3):e30. doi: 10.5395/rde.2025.50.e30. Epub 2025 Aug 8.
The aim of this study was to create a rapid admixture of mineral trioxide aggregate (MTA) and silver nanoparticles (AgNPs) for chairside use in clinical settings to remediate the challenges associated with root canal treatment and pulp capping.
Synthesized AgNPs at ratios of 10 and 25% were added to commercially available MTA to create an admixture. The admixture was subjected to structural and morphological assessment using X-ray diffraction analysis (XRD), Fourier transform infrared (FT-IR) analysis, Raman spectroscopy, and scanning electron microscopy. Antioxidant activity was measured using the hydroxyl radical scavenging assay. A significance level of 0.05 was applied to determine statistical differences.
The addition of AgNPs decreased the carbonate peak intensity in XRD and FT-IR. The rod-like morphology of MTA was changed to a flake-like morphology with the addition of AgNPs. Antibacterial efficacy enhanced proportionally with the augmentation of AgNPs concentration.
The creation of rapid admixture of MTA and AgNPs during chairside use in clinical settings can deliver beneficial characteristics of enhanced morphological features favoring mineralization and profound antibacterial effects to overcome the challenges associated with root canal treatment and pulp capping.
本研究的目的是制备一种用于临床椅旁操作的三氧化矿物凝聚体(MTA)与银纳米颗粒(AgNPs)的快速混合物,以应对与根管治疗和牙髓盖髓相关的挑战。
将比例为10%和25%的合成AgNPs添加到市售MTA中制成混合物。使用X射线衍射分析(XRD)、傅里叶变换红外(FT-IR)分析、拉曼光谱和扫描电子显微镜对该混合物进行结构和形态评估。使用羟基自由基清除试验测量抗氧化活性。应用0.05的显著性水平来确定统计学差异。
添加AgNPs降低了XRD和FT-IR中碳酸盐峰的强度。添加AgNPs后,MTA的棒状形态变为片状形态。抗菌效果随AgNPs浓度的增加而成比例增强。
在临床椅旁操作过程中制备MTA与AgNPs的快速混合物,可呈现有利于矿化的增强形态特征和显著抗菌效果等有益特性,以克服与根管治疗和牙髓盖髓相关的挑战。