Huang Xiaohui, Ou Yangjing, Tang Lin, Zhou Wei, Wang Taoli, Tan Miduo
Department of Breast Surgery, Zhuzhou Hospital Affiliated to Xiangya School of Medicine, Central South University, Zhuzhou, Hunan 412000, P.R. China.
Department of Infectious Diseases, Zhuzhou Hospital Affiliated to Xiangya School of Medicine, Central South University, Zhuzhou, Hunan 412000, P.R. China.
Oncol Lett. 2025 Aug 25;30(5):495. doi: 10.3892/ol.2025.15241. eCollection 2025 Nov.
Adenoid cystic carcinoma of the breast (ACCB) is a rare and distinct form of triple-negative breast cancer, accounting for only 0.06-0.1% of all breast cancers. ACCB is characterized by a favorable prognosis and can be divided into three subtypes: Classical, solid and high-grade transformation. The classical type is the most common and has the least aggressive biological behavior, with rare occurrences of metastasis. By contrast, patients with the solid and high-grade transformation types are more likely to experience local recurrence and distant metastasis. The present report describes a rare case of hepatic metastasis in classical ACCB, and discusses its treatment and follow-up. Additionally, the current advancements in the management of ACCB are reviewed to provide insights for further understanding and clinical guidance.
乳腺腺样囊性癌（ACCB）是三阴性乳腺癌中一种罕见且独特的类型，仅占所有乳腺癌的0.06 - 0.1%。ACCB的特点是预后良好，可分为三种亚型：经典型、实体型和高级别转化型。经典型最为常见，生物学行为侵袭性最小，转移罕见。相比之下，实体型和高级别转化型患者更易发生局部复发和远处转移。本报告描述了一例经典型ACCB肝转移的罕见病例，并讨论了其治疗及随访情况。此外，还综述了ACCB管理方面的当前进展，以提供进一步理解和临床指导的见解。
