Guo Yi, Wu Yibo, Fan Siyuan, Wang Haibo
Peking University First Hospital Peking University Beijing China.
Clinical Research Institute Institute of Advanced Clinical Medicine Peking University Beijing China.
MedComm (2020). 2025 Sep 1;6(9):e70366. doi: 10.1002/mco2.70366. eCollection 2025 Sep.
This study aimed to estimate the prevalence of adverse childhood experiences (ACEs) and explore their associations with mental health among Chinese adults. This population-based, cross-sectional survey was conducted in China in 2023. Data on participants' ACEs, depressive symptoms, anxiety symptoms, suicidal ideation, and other information were collected among participants who were selected using multi-stage stratified quota random sampling. Of 30,054 participants, 26.0% (7809/30,054) reported at least one ACE. The prevalence of major depression symptoms, moderate or severe anxiety symptoms, and suicidal ideation were 19.5%, 12.7%, and 21.7%, respectively. There was a dose‒response relationship between the cumulative number of ACEs and mental health among Chinese adults. Compared to those with no ACEs, the adjusted odds ratios (ORs) and 95% confidence interval for major depression symptoms were 1 ACE: 1.340 (1.226‒1.465), 2 ACEs: 1.769 (1.588‒1.971), 3 ACEs: 2.172 (1.909‒2.472), and ≥4 ACEs: 3.084 (2.712‒3.507). The ORs for anxiety symptoms of 1, 2, 3, and ≥4 ACEs were 1.262 (1.135‒1.403), 1.714 (1.513‒1.942), 2.119 (1.831‒2.452), and 2.890 (2.512‒3.325). The ORs for suicidal ideation were 1.056 (0.966‒1.154), 1.324 (1.188‒1.477), 1.470 (1.287‒1.679), and 3.134 (2.761‒3.557). Sexual abuse survivors were at great risk for mental health problems. Comprehensive measures are needed to support populations affected by ACEs.
本研究旨在估计中国成年人童年不良经历（ACEs）的患病率，并探讨其与心理健康的关联。这项基于人群的横断面调查于2023年在中国开展。通过多阶段分层配额随机抽样选取参与者，收集了他们关于ACEs、抑郁症状、焦虑症状、自杀意念及其他信息的数据。在30054名参与者中，26.0%（7809/30054）报告至少有一次ACE。重度抑郁症状、中度或重度焦虑症状以及自杀意念的患病率分别为19.5%、12.7%和21.7%。中国成年人中，ACEs的累积数量与心理健康之间存在剂量反应关系。与无ACEs者相比，重度抑郁症状的调整优势比（OR）及95%置信区间为：1次ACE：1.340（1.226 - 1.465），2次ACE：1.769（1.588 - 1.971），3次ACE：2.172（1.909 - 2.472），≥4次ACE：3.084（2.712 - 3.507）。1次、2次、3次及≥4次ACE的焦虑症状OR分别为1.262（1.135 - 1.403），1.714（1.513 - 1.942），2.119（1.831 - 2.452），2.890（2.512 - 3.325）。自杀意念的OR分别为1.056（0.966 - 1.154），1.324（1.188 - 1.477），1.470（1.287 - 1.679），3.134（2.761 - 3.557）。性虐待幸存者出现心理健康问题的风险很大。需要采取综合措施来支持受ACEs影响的人群。
