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特发性纤维性肺泡炎:临床、放射学、血液学、血清学及功能检查结果与支气管肺泡灌洗中细胞分布的相关性

[Idiopathic fibrosing alveolitis: correlation of the clinical, roentgenologic, hematologic, serologic and functional findings with cell distribution in bronchoalveolar lavage].

作者信息

Vetter N

出版信息

Wien Klin Wochenschr. 1985 Dec 20;97(24):897-900.

PMID:4090518
Abstract

Bronchoalveolar lavage (BAL) in patients with diffuse idiopathic interstitial fibrosis showed a high increase in the relative number of neutrophils and a moderate increase in the relative number of lymphocytes. The relative number of neutrophils and lymphocytes found on BAL did not correlate with duration of the disease, nor with the normal to pathological auscultatory findings, nor the chest X-ray appearance of reticulonodular densities with or without alveolar filling, nor with the haematological and serological findings (moderate to high erythrocyte sedimentation rate (ESR), normal to pathological alpha 1, alpha 2 and beta globulin and LDH), nor with the moderate to high reduction in vital capacity and pulmonary compliance. Examination of the BAL cellular distribution is a useful supplement to the determination of conventional parameters in the diagnosis of diffuse idiopathic interstitial fibrosis.

摘要

弥漫性特发性间质性纤维化患者的支气管肺泡灌洗(BAL)显示,中性粒细胞相对数量显著增加,淋巴细胞相对数量中度增加。BAL中发现的中性粒细胞和淋巴细胞相对数量与疾病持续时间无关,与正常至病理性的听诊结果无关,与有无肺泡填充的网状结节密度的胸部X线表现无关,与血液学和血清学检查结果(中度至高度红细胞沉降率(ESR)、正常至病理性的α1、α2和β球蛋白及乳酸脱氢酶)无关,也与肺活量和肺顺应性的中度至高度降低无关。BAL细胞分布检查是诊断弥漫性特发性间质性纤维化时确定传统参数的一项有用补充。

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