新墨西哥州祖尼印第安人的癌症发病率。
Cancer incidence in the Zuni Indians of New Mexico.
作者信息
Sorem K A
出版信息
Yale J Biol Med. 1985 Sep-Oct;58(5):489-96.
The total age-adjusted incidence of cancer in the Zuni Indians of New Mexico was significantly lower than that of the New Mexico Anglo population during the period 1969-1982. Specific sites at which the Zunis had a significantly lower number of cases than expected, based on the rates for Anglos, are: colon, rectum and anus, lung, breast, endometrium, melanoma of the skin, pancreas, and the leukemias. Sites at which the Zunis had a higher number of cases than expected are stomach and gallbladder. The Zunis have a pattern of occurrence of cancer that is similar to other American Indians of New Mexico (Navajo, Apache, and Pueblo); however, rates of lung, colonic, and pancreatic cancer among the Zunis are significantly lower. The occurrence and anatomic distribution of cancer among the Zunis may be the result of cultural and environmental conditions or genetic influences. Further studies may clarify the risk factors which contribute to this pattern of disease.
1969年至1982年期间，新墨西哥州祖尼印第安人的年龄调整后癌症总发病率显著低于新墨西哥州的盎格鲁人群。基于盎格鲁人的发病率，祖尼人病例数明显低于预期的特定部位包括：结肠、直肠和肛门、肺、乳腺、子宫内膜、皮肤黑色素瘤、胰腺以及白血病。祖尼人病例数高于预期的部位是胃和胆囊。祖尼人的癌症发病模式与新墨西哥州的其他美洲印第安人（纳瓦霍人、阿帕奇人和普韦布洛人）相似；然而，祖尼人肺癌、结肠癌和胰腺癌的发病率显著较低。祖尼人癌症的发生情况及其解剖分布可能是文化和环境条件或基因影响的结果。进一步的研究可能会阐明导致这种疾病模式的风险因素。
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