Wiggins C L, Becker T M, Key C R, Samet J M
New Mexico Tumor Registry, University of New Mexico School of Medicine, Albuquerque 87131.
Cancer Res. 1989 Mar 15;49(6):1595-9.
Stomach cancer incidence rates vary by ethnic group in New Mexico, with American Indians and Hispanic Whites at higher risk than the state's non-Hispanic White population. To further characterize the descriptive epidemiology of this disease in New Mexico, we investigated temporal trends in stomach cancer mortality and incidence rates. Stomach cancer mortality rates declined over a 25-year period (1958-1982) among New Mexico's Hispanic and non-Hispanic Whites. Birth cohort analysis suggests that much of the decline was achieved prior to 1968. Stomach cancer mortality rates did not drop among American Indians during the same period. Stomach cancer incidence rates remained constant for Hispanic Whites, non-Hispanic Whites, and American Indian males over a 13-year period (1969-1982), but more than doubled among American Indian females. Although environmental factors have been implicated in the etiology of stomach cancer, little is currently known about the distribution of such risk factors among the ethnic groups described in this report. The environmental and biological correlates of sex, ethnicity, and socioeconomic status that determine stomach cancer risk merit further investigation in New Mexico.
在新墨西哥州,胃癌发病率因种族而异,美洲印第安人和西班牙裔白人比该州非西班牙裔白人面临更高的风险。为了进一步描述该疾病在新墨西哥州的描述性流行病学特征,我们调查了胃癌死亡率和发病率的时间趋势。在25年期间(1958 - 1982年),新墨西哥州的西班牙裔和非西班牙裔白人的胃癌死亡率有所下降。出生队列分析表明,大部分下降发生在1968年之前。同期,美洲印第安人的胃癌死亡率并未下降。在13年期间(1969 - 1982年),西班牙裔白人、非西班牙裔白人以及美洲印第安男性的胃癌发病率保持不变,但美洲印第安女性的发病率增加了一倍多。尽管环境因素被认为与胃癌病因有关,但目前对于本报告中所描述的种族群体中此类风险因素的分布知之甚少。在新墨西哥州,决定胃癌风险的性别、种族和社会经济地位的环境及生物学关联值得进一步研究。