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[嗅球容积测定——嗅觉障碍客观化的一个组成部分]

[Volumetry of the olfactory bulb - One component in the objectification of disorders of the sense of smell].

作者信息

Keweloh Stefanie, Nebel Jörg-Michael, Overhoff Daniel, Waldeck Stephan

机构信息

Klinik für diagnostische und interventionelle Radiologie und Neuroradiologie, Bundeswehrzentralkrankenhaus Koblenz, Rübenacher Str. 170, 56072, Koblenz, Deutschland.

Klinik für Hals-Nasen-Ohrenheilkunde, Bundeswehrzentralkrankenhaus Koblenz, Koblenz, Deutschland.

出版信息

HNO. 2025 Sep 4. doi: 10.1007/s00106-025-01650-z.

Abstract

Disorders of olfaction are a frequent reason for an assessment in otorhinolaryngology. Particularly when the results of subjective and/or objective olfactometry are inconclusive, additional objective findings are required to verify disorders of the sense of smell. Based on practical experience and considering the current literature, this article is intended as an aid in the preparation of supplementary radiological reports. The importance of comprehensive up to date standard imaging including olfactory bulb volumetry in addition to a detailed medical history and, if applicable, previous findings should be emphasized. In addition to the documentation of alterations in the anatomical structures involved in olfaction, which support the reported disorders in the sense of smell, special neuroradiological examination sequences for the visualization of the olfactory bulb, including a volumetric measurement of the same, can provide an objective component for the assessment of sometimes only subjectively existing disorders of the sense of smell. In the majority of cases no valid comparative volumetry can be derived from a possibly pre-existing imaging study. Therefore, a comparison with olfactory bulb reference values, determined in studies for the presumed etiology and the extent of the disorder reported/determined by olfactometry is the only way to put the olfactory bulb volume in an almost objective relationship to the function of the sense of smell reported and/or determined by olfactometry.

摘要

嗅觉障碍是耳鼻喉科评估的常见原因。特别是当主观和/或客观嗅觉测量结果不明确时,需要额外的客观发现来证实嗅觉障碍。基于实践经验并参考当前文献,本文旨在辅助编写补充放射学报告。除了详细的病史以及(如适用)先前的检查结果外,还应强调全面的最新标准成像检查的重要性,包括嗅球容积测量。除了记录嗅觉相关解剖结构的改变以支持所报告的嗅觉障碍外,用于可视化嗅球的特殊神经放射学检查序列,包括对其进行容积测量,可为评估有时仅主观存在的嗅觉障碍提供客观依据。在大多数情况下,无法从可能已有的影像学检查中得出有效的对比容积测量结果。因此,将嗅球体积与嗅觉测量报告/确定的假定病因和障碍程度研究中确定的嗅球参考值进行比较,是使嗅球体积与嗅觉测量报告和/或确定的嗅觉功能建立几乎客观关系的唯一方法。

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