在肿瘤患者中疗程较短也更好吗？一项针对在门诊肿瘤诊所接受治疗的实体瘤患者单纯性感染的短疗程与长疗程抗生素治疗的回顾性队列研究。
Is Shorter Better in Oncology Patients, Too? A Retrospective Cohort Study of Short- Versus Long-Course Antibiotic Therapy for Uncomplicated Infections in Solid Tumor Patients Receiving Care in Ambulatory Oncology Clinics.
作者信息
Arena Christen J, El-Tatari Beisan, Lovric Kristen, Greenlee Sage B, Kenney Rachel M, Gadgeel Shirish M, Patterson Katelyn, Shallal Anita B, Alangaden George J, Davis Susan L, Veve Michael P
机构信息
Department of Pharmacy, Henry Ford Hospital, Detroit, Michigan, USA.
Department of Pharmacy Practice, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, Michigan, USA.
出版信息
Open Forum Infect Dis. 2025 Aug 21;12(9):ofaf505. doi: 10.1093/ofid/ofaf505. eCollection 2025 Sep.
Abstract
This retrospective cohort study evaluated short- versus long-course antibiotics for uncomplicated infections in ambulatory solid tumor patients. Among 303 patients, outcomes were similar between groups, including infection recurrence, treatment delays, and adverse events. Short-course therapy was not associated with worse outcomes, suggesting it may be a viable alternative.
摘要
这项回顾性队列研究评估了门诊实体瘤患者单纯性感染采用短疗程与长疗程抗生素治疗的效果。在303名患者中，两组之间的结果相似，包括感染复发、治疗延迟和不良事件。短疗程治疗与较差的结果无关，表明它可能是一种可行的替代方案。
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