Ahmadi Hossein, Zolfigol Mohammad Ali, Hajjami Maryam, Zarei Mahmoud, Hosseinifard Mojtaba, Gu Yanlong
Department of Organic Chemistry, Faculty of Chemistry and Petroleum Sciences, Bu-Ali Sina University PO Box 6517838683 Hamedan Iran
Department of Chemistry, Faculty of Science, University of Qom Qom 37185-359 Iran
RSC Adv. 2025 Sep 3;15(38):31674-31682. doi: 10.1039/d5ra03078a. eCollection 2025 Aug 29.
The post-synthesis of metal-organic frameworks (MOFs) plays a valuable role in enhancing their properties and functionalities. Herein a pillared layer mixed ligand metal-organic framework, derived (DMOFs) from 2-aminoterephthalic acid (BDC-NH) as an -donor and 1,4-diazabicyclo[2.2.2]octane (DABCO) as a -donor linker based on Zr as a metal, which is functionalized with Cu(OAc) as a high-efficiency heterogonous catalyst for the synthesis of pyrazolo[3,4-]pyridine derivatives. This presented work emphasizes the importance of the designability of an MOF and its multiple applications in organic chemistry, especially the synthesis of biologically active candidate compounds while considering the green chemistry principles.
金属有机框架材料（MOFs）的后合成在增强其性能和功能方面发挥着重要作用。在此，一种基于锆作为金属的柱撑层混合配体金属有机框架材料（DMOFs），它由作为π-供体的2-氨基对苯二甲酸（BDC-NH）和作为μ-供体连接体的1,4-二氮杂双环[2.2.2]辛烷（DABCO）衍生而来，并用醋酸铜（Cu(OAc)）进行功能化，作为合成吡唑并[3,4-b]吡啶衍生物的高效非均相催化剂。这项工作强调了MOF的可设计性及其在有机化学中的多种应用的重要性，特别是在考虑绿色化学原则的同时合成生物活性候选化合物。
