Department of Organic Chemistry, Faculty of Chemistry, Bu-Ali-Sina University, Hamedan, 6517838965, Iran.
Department of Chemistry, Faculty of Science, University of Qom, Qom, 37185-359, Iran.
Sci Rep. 2023 Jun 9;13(1):9388. doi: 10.1038/s41598-023-34172-1.
In this research article, Zr-MOFs based copper complex as a novel heterogeneous and porous catalyst was designed and prepared. The structure of catalyst has verified by various techniques such as FT-IR, XRD, SEM, N adsorption-desorption isotherms (BET), EDS, SEM-elemental mapping, TG and DTG analysis. UiO-66-NH/TCT/2-amino-Py@Cu(OAc) was used as an efficient catalyst in the synthesis of pyrazolo[3,4-b]pyridine-5-carbonitrile derivatives. The aromatization of titled molecules is performed via a cooperative vinylogous anomeric-based oxidation both under air and inert atmospheres. The unique properties of the presented method are short reaction time, high yield, reusability of catalyst, synthesis of desired product under mild and green condition.
在这项研究文章中，设计并制备了一种基于 Zr-MOFs 的新型异质多孔铜配合物催化剂。通过各种技术，如傅里叶变换红外光谱（FT-IR）、X 射线衍射（XRD）、扫描电子显微镜（SEM）、氮气吸附-脱附等温线（BET）、能谱（EDS）、SEM 元素映射、热重分析（TG）和差热分析（DTG）等，对催化剂的结构进行了验证。UiO-66-NH/TCT/2-氨基-Py@Cu(OAc) 被用作一种高效的催化剂，用于合成吡唑并[3,4-b]吡啶-5-甲腈衍生物。通过协同 vinylogous anomeric-based 氧化反应，在空气和惰性气氛下都能实现标题分子的芳构化。所提出的方法具有反应时间短、产率高、催化剂可重复使用、在温和环保条件下合成目标产物等独特性质。
