Sottano de Russo E Y, Ortiz A M, Cassone E
Acta Gastroenterol Latinoam. 1985;15(1):1-5.
Iron absorption in dogs without pancreatic secretion was studied measuring the percentage of radioactivity retained in red cells. Two groups were treated con 59Fe (5 microCi), given in the stomach: one group control and other undergoing pancreatic duct ligation. Increased absorption was observed in the last group. The influence of secretion on iron absorption, after administration of 60 mg of Fe (as ferrous sulphate solution pH 4.5), was also studied in three groups of dogs, treated with 18 Clinical Units of secretin. In one group, the pancreatic secretion was extracted from intestine by putting a catheter in the pancreatic duct. In the other two, the pancreatic duct remained normal, one with and other without the iron dose (control). A possible inhibitory effect of secretin on iron absorption was observed. Plasma Iron values remained without changes one hour after the iron administration, as well as TIBC, % saturation and transferrin values.
通过测量红细胞中保留的放射性百分比，研究了无胰腺分泌的犬类对铁的吸收情况。两组犬经胃给予59Fe（5微居里）进行处理：一组为对照组，另一组进行胰管结扎。观察到后一组的铁吸收增加。在三组犬中，给予60毫克铁（以pH值为4.5的硫酸亚铁溶液形式）后，还研究了分泌素对铁吸收的影响，这三组犬均用18临床单位的促胰液素进行处理。在一组中，通过将导管插入胰管从肠道提取胰腺分泌物。在另外两组中，胰管保持正常，一组给予铁剂量，另一组不给予（对照组）。观察到促胰液素对铁吸收可能有抑制作用。给予铁后一小时，血浆铁值以及总铁结合力、饱和度百分比和转铁蛋白值均无变化。
