Waki Masayuki, Fujisaki Akira, Usami Shunya, Muraoka Kei, Hakamata Yasuhiro, Kanda Yuka, Sugiura Kota, Yoshida Masashi, Otsuki Yoshiro, Yoneda Tatsuaki
Department of Urology Seirei Hamamatsu General Hospital Hamamatsu Japan.
Department of Pathology Seirei Hamamatsu General Hospital Hamamatsu Japan.
IJU Case Rep. 2025 Aug 21;8(5):539-543. doi: 10.1002/iju5.70088. eCollection 2025 Sep.
Primary squamous cell carcinoma of the prostate accounts for < 1% of prostate cancers.
A 70-year-old man with no urinary symptoms and a normal prostate-specific antigen of 0.96 ng/mL was referred for abnormal prostate uptake on positron emission tomography-computed tomography. He was diagnosed with locally advanced squamous cell carcinoma of the prostate with lymph node metastasis. Robot-assisted radical prostatectomy and adjuvant chemoradiotherapy were administered. The patient remained in complete remission at 18 months postoperatively.
Squamous cell carcinoma of the prostate should be suspected based on positron emission tomography-computed tomography prostate uptake. Robot-assisted radical prostatectomy may be feasible for locally advanced squamous cell carcinoma of the prostate; genetic profiling should be considered to identify targeted therapies.
前列腺原发性鳞状细胞癌占前列腺癌的比例小于1%。
一名70岁男性，无泌尿系统症状，前列腺特异性抗原正常，为0.96 ng/mL，因正电子发射断层扫描-计算机断层扫描显示前列腺摄取异常而前来就诊。他被诊断为局部晚期前列腺鳞状细胞癌伴淋巴结转移。实施了机器人辅助根治性前列腺切除术及辅助放化疗。患者术后18个月仍处于完全缓解状态。
基于正电子发射断层扫描-计算机断层扫描显示的前列腺摄取情况，应怀疑前列腺鳞状细胞癌。机器人辅助根治性前列腺切除术对于局部晚期前列腺鳞状细胞癌可能可行；应考虑进行基因检测以确定靶向治疗方案。
