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基因组报告:百慕大大型陆地蜗牛(软体动物门:腹足纲)的基因组组装证实了祖先基因组加倍。

Genome Report: genome assembly of the greater Bermuda land snail, (Mollusca: Gastropoda), confirms ancestral genome duplication.

作者信息

Winingear Stevie, Outerbridge Mark, Garcia Gerardo, Stone Anne C, Wilson Melissa A, Polly P David

机构信息

School of Human Evolution and Social Change, Arizona State University, Tempe, AZ, 85281 USA.

Center for Evolution and Medicine, Arizona State University, Tempe, AZ, 85281 USA.

出版信息

bioRxiv. 2025 Aug 25:2025.08.21.671598. doi: 10.1101/2025.08.21.671598.

Abstract

the greater Bermuda land snail, is a critically endangered species and one of only two extant members in its genus. These snails are one of Bermuda's few endemic animal clades and their rich fossil record was the basis for the punctuated equilibria model of speciation. Once thought extinct, recent conservation efforts have focused on the recovery of the species, yet no genomic information or other molecular sequences have been available to inform these initiatives. We present a high-quality, annotated genome for generated using PacBio long read and Omni-C short read sequencing. The resulting assembly is approximately 1.36 Gb with a scaffold N50 of 44.t Mb and 31 chromosome-length scaffolds. Nearly 43 percent of the genome was identified as repeat content. This assembly will serve as a resource for the conservation and study of , and its only close extant and also critically endangered relative, . Additionally, this genome adds to the growing body of data needed for a more complete understanding of gastropod evolution and for evolutionary processes in general.

摘要

百慕大大蜗牛是一种极度濒危物种,也是其属中仅存的两个成员之一。这些蜗牛是百慕大少数特有的动物类群之一,它们丰富的化石记录是物种形成的间断平衡模型的基础。该物种曾一度被认为已灭绝,最近的保护工作聚焦于该物种的恢复,但此前一直没有基因组信息或其他分子序列来为这些举措提供参考。我们利用PacBio长读长测序和Omni-C短读长测序技术,为[物种名称]生成了一个高质量的注释基因组。最终的组装结果约为1.36Gb,支架N50为44.7Mb,有31个染色体长度的支架。近43%的基因组被鉴定为重复序列。这个组装结果将作为保护和研究[物种名称]及其仅存的亲缘关系最近且同样极度濒危的[另一物种名称]的资源。此外,这个基因组为更全面地理解腹足纲动物进化以及一般进化过程所需的不断增长的数据量增添了内容。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a34/12407731/e5d040f9b5ca/nihpp-2025.08.21.671598v1-f0001.jpg

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