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肯尼亚感染艾滋病毒女性的避孕方法属性偏好与使用情况的比对

Alignment of contraceptive method attribute preferences and use among Kenyan women living with HIV.

作者信息

Hardenbergh Leah, Seth Aparna, Richardson Barbra A, Farid Shiza, Udren Jenna I, Rothschild Claire W, Mwongeli Nancy, Karume Agnes K, Atieno Celestine, Moraa June, Unger Jennnifer A, Enquobahrie Daniel A, Kinuthia John, Drake Alison L

机构信息

Department of Epidemiology, University of Washington, Seattle, WA, USA.

Department of Global Health, University of Washington, Seattle, WA, USA.

出版信息

medRxiv. 2025 Aug 26:2025.08.21.25334189. doi: 10.1101/2025.08.21.25334189.

Abstract

OBJECTIVE

Understanding alignment of contraceptive preferences and method selection among women living with HIV (WLWH) may improve contraceptive counseling. We examined whether method attribute preferences aligned with method attributes used among WLWH, and identified preference clusters.

STUDY DESIGN

We used baseline data from WLWH enrolled in a cluster randomized controlled trial of a reproductive health counseling intervention in Kenya. Women using modern contraception at baseline were eligible (N=2,599). We used Poisson regression models to characterize 11 relationships between method attributes preferred vs used, and principal component analysis (PCA) to identify preferences clusters.

RESULTS

Women who preferred methods that are long-acting (adjusted Prevalence Ratio [aPR]:1.63, 95% Confidence Interval [CI]:1.19-2.24), avoid daily dosing (aPR:1.11, 95% CI:1.07-1.16), permit self-discontinuation (aPR:1.32, 95% CI:1.14-1.52), and are concealable (aPR:1.06, 95% CI:1.01-1.12) were significantly more likely to use aligned methods. Attribute preferences clustered on three dimensions: (1) avoiding heavy bleeding, weight changes, libido changes, and non-hormonal; (2) long-acting, avoiding daily dosing, permitting self-discontinuation, and avoiding intermittent bleeding; and (3) concealability without an effectiveness preference. Immediate return to fertility was modeled independently due to lack of clustering. The first dimension was positively correlated with condom use and inversely with implant use. The second was also positively correlated with condom use, and use of both implants and tubal ligation, while inversely with injectable and oral contraceptive pill use. The third was correlated with injectable use.

CONCLUSION

Method attribute preferences do not always align with methods used and may cluster in ways that cannot be satisfied by existing methods.

IMPLICATIONS

Preferences for methods that are long-acting, avoid daily dosing, and permit self-discontinuation are widely held and related to method selection, but cannot be met by a single method when held in combination. Client-centered counseling can elicit relative strength of preferences and tailor guidance accordingly, improving method satisfaction.

摘要

目的

了解感染艾滋病毒的女性(WLWH)的避孕偏好与方法选择的一致性,可能会改善避孕咨询服务。我们研究了方法属性偏好是否与WLWH中使用的方法属性一致,并确定了偏好集群。

研究设计

我们使用了参与肯尼亚一项生殖健康咨询干预措施的整群随机对照试验的WLWH的基线数据。基线时使用现代避孕方法的女性符合条件(N = 2599)。我们使用泊松回归模型来描述首选方法属性与使用方法属性之间的11种关系,并使用主成分分析(PCA)来确定偏好集群。

结果

倾向于长效方法(调整患病率比[aPR]:1.63,95%置信区间[CI]:1.19 - 2.24)、避免每日服药(aPR:1.11,95% CI:1.07 - 1.16)、允许自行停药(aPR:1.32,95% CI:1.14 - 1.52)和可隐蔽使用的方法(aPR:1.06,95% CI:1.01 - 1.12)的女性,使用相符方法的可能性显著更高。属性偏好集中在三个维度上:(1)避免大量出血、体重变化、性欲变化且非激素方法;(2)长效、避免每日服药、允许自行停药且避免间歇性出血;(3)可隐蔽性且无有效性偏好。由于缺乏聚类,独立对立即恢复生育能力进行了建模。第一个维度与避孕套使用呈正相关,与植入物使用呈负相关。第二个维度也与避孕套使用呈正相关,与植入物和输卵管结扎的使用呈正相关,而与注射剂和口服避孕药的使用呈负相关。第三个维度与注射剂使用相关。

结论

方法属性偏好并不总是与所使用的方法一致,并且可能以现有方法无法满足的方式聚类。

启示

对长效、避免每日服药和允许自行停药方法的偏好广泛存在且与方法选择相关,但当这些偏好同时存在时,单一方法无法满足。以客户为中心的咨询可以引出偏好的相对强度并据此调整指导,提高方法满意度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c461/12407609/e75778b00c36/nihpp-2025.08.21.25334189v1-f0001.jpg

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