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本文引用的文献

1
Expanding contraceptive options for PMTCT clients: a mixed methods implementation study in Cape Town, South Africa.扩大 PMTCT 服务对象的避孕选择:在南非开普敦进行的一项混合方法实施研究。
Reprod Health. 2014 Jan 10;11(1):3. doi: 10.1186/1742-4755-11-3.
2
The impact of Centering Pregnancy Group Prenatal Care on postpartum family planning.孕期集中小组产前护理对产后计划生育的影响。
Am J Obstet Gynecol. 2014 Jan;210(1):50.e1-7. doi: 10.1016/j.ajog.2013.09.001. Epub 2013 Sep 7.
3
Evaluation of an integrated services program to prevent subsequent pregnancy and birth among urban teen mothers.评估一项综合性服务计划,以防止城市青少年母亲再次怀孕和生育。
Soc Work Health Care. 2013;52(7):642-55. doi: 10.1080/00981389.2013.797538.
4
Family planning practices and pregnancy intentions among HIV-positive and HIV-negative postpartum women in Swaziland: a cross sectional survey.斯威士兰 HIV 阳性和 HIV 阴性产后妇女的计划生育实践和怀孕意愿:一项横断面调查。
BMC Pregnancy Childbirth. 2013 Jul 15;13:150. doi: 10.1186/1471-2393-13-150.
5
The effect of long-acting reversible contraception on rapid repeat pregnancy in adolescents: a review.长效可逆避孕措施对青少年反复快速妊娠的影响:综述。
J Adolesc Health. 2013 Apr;52(4 Suppl):S47-53. doi: 10.1016/j.jadohealth.2012.10.278.
6
Relationships between antenatal and postnatal care and post-partum modern contraceptive use: evidence from population surveys in Kenya and Zambia.产前和产后保健与产后现代避孕方法使用之间的关系:来自肯尼亚和赞比亚人口调查的证据。
BMC Health Serv Res. 2013 Jan 4;13:6. doi: 10.1186/1472-6963-13-6.
7
Study protocol for the Integra Initiative to assess the benefits and costs of integrating sexual and reproductive health and HIV services in Kenya and Swaziland.《评估肯尼亚和斯威士兰将性健康和生殖健康与艾滋病毒服务相结合的益处和成本的 Integra 倡议研究方案》
BMC Public Health. 2012 Nov 13;12:973. doi: 10.1186/1471-2458-12-973.
8
Intended and unintended births in the United States: 1982-2010.美国1982年至2010年的计划内生育与意外生育情况
Natl Health Stat Report. 2012 Jul 24(55):1-28.
9
The adolescent family life program: a multisite evaluation of federally funded projects serving pregnant and parenting adolescents.青少年家庭生活计划:一项针对为怀孕和育儿青少年提供服务的联邦资助项目的多地点评估。
Am J Public Health. 2012 Oct;102(10):1872-8. doi: 10.2105/AJPH.2012.300836. Epub 2012 Aug 16.
10
Education for contraceptive use by women after childbirth.产后妇女避孕方法的教育。
Cochrane Database Syst Rev. 2012 Aug 15(8):CD001863. doi: 10.1002/14651858.CD001863.pub3.

改善产后避孕措施使用情况的策略:来自非随机研究的证据

Strategies for improving postpartum contraceptive use: evidence from non-randomized studies.

作者信息

Lopez Laureen M, Grey Thomas W, Chen Mario, Hiller Janet E

机构信息

Clinical and Epidemiological Sciences, FHI 360, 359 Blackwell St, Suite 200, Durham, North Carolina, USA, 27701.

出版信息

Cochrane Database Syst Rev. 2014 Nov 27;2014(11):CD011298. doi: 10.1002/14651858.CD011298.pub2.

DOI:10.1002/14651858.CD011298.pub2
PMID:25429714
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11129846/
Abstract

BACKGROUND

Nearly two-thirds of women in their first postpartum year have an unmet need for family planning. Adolescents often have repeat pregnancies within a year of giving birth. Women may receive counseling on family planning both antepartum and postpartum. Decisions about contraceptive use made right after counseling may differ considerably from actual postpartum use. In earlier work, we found limited evidence of effectiveness from randomized trials on postpartum contraceptive counseling. For educational interventions, non-randomized studies may be conducted more often than randomized trials.

OBJECTIVES

We reviewed non-randomized studies of educational strategies to improve postpartum contraceptive use. Our intent was to examine associations between specific interventions and postpartum contraceptive use or subsequent pregnancy.

SEARCH METHODS

We searched for eligible non-randomized studies until 3 November 2014. Sources included CENTRAL, PubMed, POPLINE, and Web of Science. We also sought current trials via ClinicalTrials.gov and ICTRP. For additional citations, we examined reference lists of relevant reports and reviews.

SELECTION CRITERIA

The studies had to be comparative, i.e., have intervention and comparison groups. The educational component could be counseling or another behavioral strategy to improve contraceptive use among postpartum women. The intervention had to include contact within six weeks postpartum. The comparison condition could be another behavioral strategy to improve contraceptive use, usual care, other health education, or no intervention. Our primary outcomes were postpartum contraceptive use and subsequent pregnancy.

DATA COLLECTION AND ANALYSIS

Two authors evaluated abstracts for eligibility and extracted data from included studies. We computed the Mantel-Haenszel odds ratio (OR) for dichotomous outcomes and the mean difference (MD) for continuous measures, both with 95% Confidence Intervals (CI). Where studies used adjusted analyses for continuous outcomes, we presented the results as reported by the investigators. Due to differences in interventions and outcome measures, we did not conduct meta-analysis. To assess the evidence quality, we used the Newcastle-Ottawa Quality Assessment Scale.

MAIN RESULTS

Six studies met our inclusion criteria and included a total of 5143 women. Of three studies with self-reported pregnancy data, two showed pregnancy to be less likely in the experimental group than in the comparison group (OR 0.48, 95% CI 0.27 to 0.87) (OR 0.60, 95% CI 0.41 to 0.87). The interventions included a clinic-based counseling program and a community-based communication project.All studies showed some association of the intervention with contraceptive use. Two showed that treatment-group women were more likely to use a modern method than the control group: ORs were 1.77 (95% CI 1.08 to 2.89) and 3.08 (95% CI 2.36 to 4.02). In another study, treatment-group women were more likely than control-group women to use pills (OR 1.78, 95% CI 1.26 to 2.50) or an intrauterine device (IUD) (OR 3.72, 95% CI 1.27 to 10.86) but less likely to use and injectable method (OR 0.23, 95% CI 0.05 to 1.00). One study used a score for method effectiveness. The methods of the special-intervention group scored higher than those of the comparison group at three months (MD 13.26, 95% CI 3.16 to 23.36). A study emphasizing IUDs showed women in the intervention group were more likely to use an IUD (OR 1.79, 95% CI 1.20 to 2.69) and less likely to use no method (OR 0.48, 95% CI 0.31 to 0.75). In another study, contraceptive use was more likely among women in a health service intervention compared to women in a community awareness program at four months (OR 1.79, 95% CI 1.40 to 2.30) or women receiving standard care at 10 to 12 months (OR 2.08, 95% CI 1.58 to 2.74). That study was the only one with a specific component on the lactational amenorrhea method (LAM) that had sufficient data on LAM use. Women in the health service group were more likely than those in the community awareness group to use LAM (OR 41.36, 95% CI 10.11 to 169.20).

AUTHORS' CONCLUSIONS: We considered the quality of evidence to be very low. The studies had limitations in design, analysis, or reporting. Three did not adjust for potential confounding and only two had sufficient information on intervention fidelity. Outcomes were self reported and definitions varied for contraceptive use. All studies had adequate follow-up periods but most had high losses, as often occurs in contraception studies.

摘要

背景

在产后第一年,近三分之二的女性有未满足的计划生育需求。青少年往往在分娩后一年内再次怀孕。女性在产前和产后可能会接受计划生育咨询。咨询后立即做出的避孕使用决定可能与实际产后使用情况有很大差异。在早期的研究中,我们发现随机试验中关于产后避孕咨询有效性的证据有限。对于教育干预措施,非随机研究可能比随机试验更常进行。

目的

我们回顾了关于改善产后避孕使用的教育策略的非随机研究。我们的目的是研究特定干预措施与产后避孕使用或随后怀孕之间的关联。

检索方法

我们检索了截至2014年11月3日的符合条件的非随机研究。来源包括Cochrane系统评价数据库、PubMed、人口信息数据库和科学引文索引。我们还通过ClinicalTrials.gov和国际临床试验注册平台查找当前的试验。为获取更多参考文献,我们查阅了相关报告和综述的参考文献列表。

选择标准

研究必须具有可比性,即有干预组和对照组。教育内容可以是咨询或其他行为策略,以提高产后女性的避孕使用率。干预措施必须包括在产后六周内进行接触。对照条件可以是另一种提高避孕使用率的行为策略、常规护理、其他健康教育或无干预。我们的主要结局是产后避孕使用情况和随后的怀孕情况。

数据收集与分析

两位作者评估摘要的合格性,并从纳入研究中提取数据。我们计算了二分结局的Mantel-Haenszel比值比(OR)和连续测量的平均差(MD),两者均带有95%置信区间(CI)。当研究对连续结局使用调整分析时,我们按研究者报告的结果呈现。由于干预措施和结局测量的差异,我们未进行荟萃分析。为评估证据质量,我们使用了纽卡斯尔-渥太华质量评估量表。

主要结果

六项研究符合我们的纳入标准,共纳入5143名女性。在三项有自我报告怀孕数据的研究中,两项显示试验组怀孕的可能性低于对照组(OR 0.48,95% CI 0.27至0.87)(OR 0.60,95% CI 0.41至0.87)。干预措施包括基于诊所的咨询项目和基于社区的沟通项目。所有研究均显示干预措施与避孕使用之间存在某种关联。两项研究表明,治疗组女性比对照组更有可能使用现代避孕方法:OR分别为1.77(95% CI 1.08至2.89)和3.08(95% CI 2.36至4.02)。在另一项研究中,治疗组女性比对照组女性更有可能使用口服避孕药(OR 1.78,95% CI 1.26至2.50)或宫内节育器(IUD)(OR 3.72,95% CI 1.27至10.86),但使用注射方法的可能性较小(OR 0.23,95% CI 0.05至1.00)。一项研究使用了方法有效性评分。特殊干预组的方法在三个月时得分高于对照组(MD 13.26,95% CI 3.16至23.36)。一项强调宫内节育器的研究表明,干预组女性更有可能使用宫内节育器(OR 1.79,95% CI 1.20至2.69),不使用任何方法的可能性较小(OR 0.48,95% CI 0.31至0.75)。在另一项研究中,与社区意识项目组的女性相比,健康服务干预组的女性在四个月时更有可能使用避孕措施(OR 1.79,95% CI 1.40至2.30),或与接受标准护理的女性相比,在10至12个月时更有可能使用避孕措施(OR 2.08,95% CI 1.58至2.74)。该研究是唯一一项有关于哺乳期闭经法(LAM)特定内容且有足够LAM使用数据的研究。健康服务组的女性比社区意识组的女性更有可能使用LAM(OR 41.36,95% CI 10.11至169.20)。

作者结论

我们认为证据质量非常低。这些研究在设计、分析或报告方面存在局限性。三项研究未对潜在混杂因素进行调整,只有两项研究有足够的干预保真度信息。结局是自我报告的,避孕使用的定义各不相同。所有研究都有足够的随访期,但大多数研究的失访率很高这在避孕研究中经常出现。