Andriessen Charlotte, Blom Marieke T, van Hoek Beryl A C E, de Boer Anna W, Denig Petra, Herings Ron, de Rooij-Peek Angela, van Marum Rob J, Hugtenburg Jacqueline G, van Raalte Daniël, van Bloemendaal Liselotte, Nijpels Giel, Westerman Marjan J, Vos Rimke C, Elders Petra J M
Department of General Practice, Amsterdam University Medical Center, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands.
Amsterdam Public Health Research Institute, 1105 AZ Amsterdam, The Netherlands.
Fam Pract. 2025 Aug 14;42(5). doi: 10.1093/fampra/cmaf064.
Elderly patients with Type 2 diabetes (T2D) are frequently overtreated with glucose-lowering medication.
This feasibility study evaluated the implementation of a deprescribing programme (DPP) for general practices, consisting of education, a patient selection tool, practice visits, and an expert support panel, before scaling it in a randomized controlled trial.
Quantitative evaluation included the number of patients with T2D eligible for deprescribing using medical records and study progress data. Qualitative evaluation entailed the analysis of minutes made during training, and interviews with health care providers (HCPs). The extended normalization process theory guided analysis.
In 10 practices, 55 out of 65 eligible patients were deprescribed glucose-lowering medication, with 22 restarts. Most execution steps were perceived as the practice nurse's responsibility, whereas the general practitioner needed to approve the deprescribing. Practice nurses found the educational training, including peer-to-peer sessions and practice visits, supportive of integrating deprescribing into practice. DPP procedures and tasks not part of the regular care process were not consistently performed. The DPP was adapted to minimize study tasks for HCPs and align study procedures to existing routine procedures.
Implementation of a DPP in general practice requires education, practice visits, and alignment of DPP components to regular care.
老年2型糖尿病(T2D)患者经常接受过度的降糖药物治疗。
这项可行性研究在将一项针对普通诊所的减药计划(DPP)推广到随机对照试验之前,对其实施情况进行了评估,该计划包括教育、患者选择工具、诊所访视和专家支持小组。
定量评估包括使用病历和研究进展数据确定符合减药条件的T2D患者数量。定性评估包括分析培训期间的记录以及对医疗保健提供者(HCP)的访谈。扩展的规范化过程理论指导分析。
在10家诊所中,65名符合条件的患者中有55名停用了降糖药物,其中22名再次开始用药。大多数执行步骤被视为执业护士的职责,而全科医生需要批准减药。执业护士发现教育培训,包括同行交流和诊所访视,有助于将减药纳入临床实践。不属于常规护理流程的DPP程序和任务执行情况不一致。对DPP进行了调整,以尽量减少HCP的研究任务,并使研究程序与现有常规程序保持一致。
在普通诊所实施DPP需要进行教育、诊所访视,并使DPP各组成部分与常规护理保持一致。