Department of Clinical Pharmacology and Pharmacy, Amsterdam UMC, Location VUmc, Amsterdam, The Netherlands.
Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Drugs Aging. 2022 Mar;39(3):209-221. doi: 10.1007/s40266-021-00918-7. Epub 2022 Feb 21.
Benefits and risks of preventive medication change over time for ageing patients and deprescribing of medication may be needed. Deprescribing of cardiovascular and antidiabetic drugs can be challenging and is not widely implemented in daily practice.
The aim of this study was to identify barriers and enablers of deprescribing cardiometabolic medication as seen by healthcare providers (HCPs) of different disciplines, and to explore their views on their specific roles in the process of deprescribing.
Three focus groups with five general practitioners, eight pharmacists, three nurse practitioners, two geriatricians, and two elder care physicians were conducted in three cities in The Netherlands. Interviews were recorded and transcribed verbatim. Directed content analysis was performed on the basis of the Theoretical Domains Framework. Two researchers independently coded the data.
Most HCPs agreed that deprescribing of cardiometabolic medication is relevant but that barriers include lack of evidence and expertise, negative beliefs and fears, poor communication and collaboration between HCPs, and lack of resources. Having a guideline was considered an enabler for the process of deprescribing of cardiometabolic medication. Some HCPs feared the consequences of discontinuing cardiovascular or antidiabetic medication, while others were not motivated to deprescribe when the patients experienced no problems with their medication. HCPs of all disciplines stated that adequate patient communication and involving the patients and relatives in the decision making enables deprescribing. Barriers to deprescribing included the use of medication initiated by specialists, the poor exchange of information, and the amount of time it takes to deprescribe cardiometabolic medication. The HCPs were uncertain about each other's roles and responsibilities. A multidisciplinary approach including the pharmacist and nurse practitioner was seen as the best way to support the process of deprescribing and address barriers related to resources.
HCPs recognized the importance of deprescribing cardiometabolic medication as a medical decision that can only be made in close cooperation with the patient. To successfully accomplish the process of deprescribing they strongly recommended a multidisciplinary approach.
随着患者年龄的增长,预防用药的益处和风险可能会发生变化,可能需要调整用药或停药。心血管和抗糖尿病药物的停药可能具有挑战性,并且在日常实践中尚未广泛实施。
本研究旨在确定不同专业的医疗保健提供者(HCP)在停药方面所面临的障碍和促进因素,并探讨他们对自己在停药过程中的特定角色的看法。
在荷兰的三个城市中进行了三次焦点小组讨论,参与者包括五名全科医生、八名药剂师、三名执业护士、两名老年病医生和两名老年护理医生。访谈进行了录音,并逐字记录。根据理论领域框架进行了定向内容分析。两位研究人员独立对数据进行编码。
大多数 HCP 认为,停止使用心血管代谢药物是合理的,但存在一些障碍,包括缺乏证据和专业知识、负面信念和恐惧、HCP 之间沟通和协作不佳、以及资源不足。有一个指南被认为是促进心血管代谢药物停药过程的一个因素。一些 HCP 担心停止使用心血管或抗糖尿病药物会带来后果,而另一些 HCP 在患者没有药物问题时则没有动力停药。所有学科的 HCP 都表示,充分的患者沟通以及让患者和家属参与决策有助于停药。停药的障碍包括专科医生开具的药物、信息交流不畅以及停止使用心血管代谢药物所需的时间。HCP 对彼此的角色和责任存在不确定性。多学科方法包括药剂师和执业护士,被认为是支持停药过程和解决与资源相关障碍的最佳方法。
HCP 认识到停止使用心血管代谢药物作为一项医疗决策的重要性,该决策只能在与患者密切合作的情况下做出。为了成功完成停药过程,他们强烈建议采用多学科方法。