作者对《关于持续局部麻醉药输注安全性评估的思考》的回复。 - Suppr

The author reply to "Considerations regarding the safety evaluation of continuous local anesthetic infusion".

作者信息

Sato Yuna, Sugino Shigekazu

机构信息

Department of Anesthesiology and Perioperative Medicine, Tohoku University Graduate School of Medicine, 2-1, Seiryo-Machi, Aoba-Ku, Sendai, 980-8575, Japan.

出版信息

J Anesth. 2025 Sep 5. doi: 10.1007/s00540-025-03572-0.

DOI:10.1007/s00540-025-03572-0

PMID:40911082

Abstract

摘要

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The author reply to "Considerations regarding the safety evaluation of continuous local anesthetic infusion".作者对《关于持续局部麻醉药输注安全性评估的思考》的回复。

J Anesth. 2025 Sep 5. doi: 10.1007/s00540-025-03572-0.

Dexamethasone and dexmedetomidine as adjuvants to local anesthetic mixture in erector spinae plane block combined with serratus anterior plane block for thoracoscopic surgery: a prospective, randomized controlled trial.地塞米松和右美托咪定作为局部麻醉混合剂的佐剂用于竖脊肌平面阻滞联合前锯肌平面阻滞的胸腔镜手术：一项前瞻性随机对照试验。

Minerva Anestesiol. 2025 Jun 23. doi: 10.23736/S0375-9393.25.18895-0.

Combining ropivacaine transversus abdominis plane block with intravenous lidocaine infusion in adults undergoing colorectal cancer surgery: an open-label, dose-escalation exploratory trial.在接受结直肠癌手术的成人中，将罗哌卡因腹横肌平面阻滞与静脉输注利多卡因联合应用：一项开放标签、剂量递增的探索性试验。

BMC Anesthesiol. 2025 Jul 22;25(1):357. doi: 10.1186/s12871-025-03225-5.

Relative effects of serratus anterior plane block performed with dexmedetomidine combined with ropivacaine or ropivacaine alone on quality of recovery in children undergoing ear reconstruction.右美托咪定复合罗哌卡因与单纯罗哌卡因行竖脊肌平面阻滞对行耳廓再造术患儿苏醒质量的影响。

J Plast Reconstr Aesthet Surg. 2024 Nov;98:1-9. doi: 10.1016/j.bjps.2024.08.060. Epub 2024 Aug 17.

Serratus Anterior Plane Block with Methylene Blue and Ropivacaine for analgesia in Prosthetic Breast Augmentation: A Randomized Controlled Trial.亚甲蓝与罗哌卡因用于假体隆胸镇痛的前锯肌平面阻滞：一项随机对照试验

Plast Reconstr Surg. 2025 Jul 29. doi: 10.1097/PRS.0000000000012344.

Analgesic efficacy and serum ropivacaine concentration of postoperative programmed intermittent bolus infusion with serratus anterior plane block in patients undergoing minimally invasive cardiac surgery: A randomized, double-blind, controlled trial.微创心脏手术患者术后前锯肌平面阻滞程序化间歇性推注的镇痛效果及血清罗哌卡因浓度：一项随机、双盲、对照试验

J Anesth. 2025 Jul 1. doi: 10.1007/s00540-025-03536-4.

Comparison of continuous Serratus Anterior Plane Block (cSAPB) with bupivacaine versus single liposomal bupivacaine block in postoperative analgesia after Video-Assisted Thoracoscopic Surgery (VATS): a randomized controlled trial.连续前锯肌平面阻滞（cSAPB）联合布比卡因与单剂量脂质体布比卡因阻滞用于电视辅助胸腔镜手术（VATS）术后镇痛的比较：一项随机对照试验

BMC Anesthesiol. 2025 Aug 8;25(1):399. doi: 10.1186/s12871-025-03249-x.

Efficacy of regional anesthesia techniques for postoperative analgesia in patients undergoing major oncologic breast surgeries: a systematic review and network meta-analysis of randomized controlled trials.区域麻醉技术在大型肿瘤乳腺手术后患者术后镇痛中的疗效：一项随机对照试验的系统评价和网络荟萃分析。

Can J Anaesth. 2022 Apr;69(4):527-549. doi: 10.1007/s12630-021-02183-z. Epub 2022 Jan 31.

Comparison of the effect of different volumes ropivacaine on deep serratus anterior plane block in patients undergoing breast surgery: a prospective randomized double-blinded trial.比较不同容量罗哌卡因对行乳腺手术患者的肋间神经后入路平面阻滞效果的前瞻性随机双盲试验。

Ann Palliat Med. 2021 Jun;10(6):6104-6111. doi: 10.21037/apm-21-199. Epub 2021 May 20.

Comparison of the pharmacokinetic variations of different concentrations of ropivacaine used for serratus anterior plane block in patients undergoing thoracoscopic lobectomy: a population pharmacokinetics analysis.胸腔镜肺叶切除术患者中不同浓度罗哌卡因用于前锯肌平面阻滞的药代动力学差异比较：群体药代动力学分析

Front Pharmacol. 2025 Mar 26;16:1540606. doi: 10.3389/fphar.2025.1540606. eCollection 2025.

本文引用的文献

Prevention of catheter-related bladder discomfort and agitation by intravesical lidocaine administration during awake craniotomy: a retrospective study.清醒开颅手术期间膀胱内注射利多卡因预防导管相关膀胱不适和躁动：一项回顾性研究。

J Anesth. 2025 Aug 28. doi: 10.1007/s00540-025-03567-x.

Considerations regarding the safety evaluation of continuous local anesthetic infusion: interpretation of blood concentration thresholds based on administration method.关于连续局部麻醉药输注安全性评估的考量：基于给药方法对血药浓度阈值的解读。

J Anesth. 2025 Aug 6. doi: 10.1007/s00540-025-03558-y.

Quadratus Lumborum Block: Analgesic Effects and Chronological Ropivacaine Concentrations After Laparoscopic Surgery.腰方肌阻滞：腹腔镜手术后的镇痛效果及罗哌卡因浓度变化

Reg Anesth Pain Med. 2016 Mar-Apr;41(2):146-50. doi: 10.1097/AAP.0000000000000349.

Chronological Changes in Ropivacaine Concentration and Analgesic Effects Between Transversus Abdominis Plane Block and Rectus Sheath Block.腹横肌平面阻滞与腹直肌鞘阻滞之间罗哌卡因浓度及镇痛效果的时间变化

Reg Anesth Pain Med. 2015 Sep-Oct;40(5):568-71. doi: 10.1097/AAP.0000000000000288.

Symptomatic local anaesthetic toxicity and plasma ropivacaine concentrations after transversus abdominis plane block for Caesarean section.剖宫产腹横肌平面阻滞致局部麻醉药中毒的症状和罗哌卡因的血浆浓度。

Br J Anaesth. 2013 Jun;110(6):996-1000. doi: 10.1093/bja/aet015. Epub 2013 Mar 1.

Central nervous and cardiovascular effects of i.v. infusions of ropivacaine, bupivacaine and placebo in volunteers.静脉输注罗哌卡因、布比卡因和安慰剂对志愿者中枢神经系统和心血管系统的影响。

Br J Anaesth. 1997 May;78(5):507-14. doi: 10.1093/bja/78.5.507.

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The author reply to "Considerations regarding the safety evaluation of continuous local anesthetic infusion".

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