Boutaleb Amine Mamoun, Boulogne Cyrille, Chenard Pierre, Martins Elie, Boukhris Marouane, Cianci Andrea, Le Bivic Louis, Jouan Jérôme, Aboyans Victor
Department of Cardiology, Dupuytren University Hospital, Limoges, France.
Department of Cardiology, Dupuytren University Hospital, Limoges, France.
JACC Case Rep. 2025 Sep 3;30(26):104881. doi: 10.1016/j.jaccas.2025.104881.
Coronary artery aneurysm (CAA) is a rare congenital or acquired coronary malformation, associated with coronary artery fistula (CAF) in approximately 15% of cases. CAA is often asymptomatic.
We report the case of a 60-year-old woman diagnosed in 2017 with a 15-mm large giant left main to left circumflex CAA. In 2024, she presented with progressive dyspnea. Multimodality imaging revealed severe mitral valve regurgitation and giant CAA associated with a distal CAF. After comprehensive evaluation, the heart team opted for mitral valve surgery and conservative CAA management. After 9-month follow-up, she remains uneventful.
Management of giant CAA is controversial. Surgery remains the gold standard treatment, yet particularly challenging. It is mainly recommended for symptomatic patients, with evidence of ischemia or a significant left-to-right shunt.
TAKE-HOME MESSAGES: Conservative therapy remains a valuable option in asymptomatic cases, provided that close follow-up is ensured. Multimodal imaging is crucial for diagnosis, management, and surveillance.
冠状动脉瘤(CAA)是一种罕见的先天性或后天性冠状动脉畸形,约15%的病例与冠状动脉瘘(CAF)相关。CAA通常无症状。
我们报告一例60岁女性病例,该患者于2017年被诊断为左主干至左旋支15毫米大的巨大冠状动脉瘤。2024年,她出现进行性呼吸困难。多模态成像显示严重二尖瓣反流以及与远端冠状动脉瘘相关的巨大冠状动脉瘤。经过全面评估,心脏团队选择进行二尖瓣手术并对冠状动脉瘤采取保守治疗。经过9个月的随访,她情况平稳。
巨大冠状动脉瘤的治疗存在争议。手术仍然是金标准治疗方法,但极具挑战性。主要推荐用于有症状的患者,有缺血证据或明显左向右分流的患者。
在确保密切随访的情况下,保守治疗在无症状病例中仍然是一种有价值的选择。多模态成像对于诊断、治疗和监测至关重要。