Palmieri G, Panu R, Asole A, De Riu P L, Farina V, Sanna L
Arch Anat Microsc Morphol Exp. 1985;74(2):111-9.
The authors studied, for the first time, the effects of 3-acetylpyridine administration on the nervous system of birds. The results were compared with those obtained in a mammal not studied yet. The data achieved from the guinea-pig confirmed substantially those got from other mammals, particularly from the rat. They pointed out the constant toxic action caused by the above drug inoculation on the central nervous system. The effects on birds are quite different: 3-AP administration, even at different doses from those employed in mammals, seldom provokes lesions of the central nervous system and the appearance of alterations does not depend on the considered species.
作者首次研究了给予3-乙酰吡啶对鸟类神经系统的影响。将结果与在一种尚未研究过的哺乳动物中获得的结果进行了比较。从豚鼠获得的数据基本上证实了从其他哺乳动物，特别是从大鼠获得的数据。他们指出了上述药物接种对中枢神经系统造成的持续毒性作用。对鸟类的影响则大不相同：即使给予与在哺乳动物中使用的剂量不同的3-AP，也很少引起中枢神经系统的损伤，而且变化的出现并不取决于所考虑的物种。
