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[MAV 2-0成髓细胞白血病病毒诱导的实验性禽骨质增生中的骨膜。与骨硬化症的鉴别诊断]

[The periosteum in experimental avian hyperostosis induced by MAV 2-0 myeloblastosis virus. Differential diagnosis from osteopetrosis].

作者信息

Graf B, Coudert F, Mazzella O, Cauchy L

出版信息

Arch Anat Microsc Morphol Exp. 1985;74(2):151-66.

PMID:4091574
Abstract

Diaphyseal tibial bones of 11-14-17 th day-old hatched chicks infected with retrovirus myeloblastic MAV 2-0 were examined by conventional optical microscopy. The characteristic lesion is osteoblastic hyperplasia with the development of spongious bone. The new formed bone contains abnormal chondroid tissue. The relation between osseous and cartilaginous tissues in this experimental model is discussed. As connective tissue took part in the constitution of this hyperostosis, this osteopathy may be considered as an hyperplastic, monodermic mesenchymatous, pluritissular tumour. The numerous works concerning the "avian hyperostosis osteopetrosis" are commented.

摘要

对感染逆转录病毒成髓细胞性MAV 2 - 0的11日龄、14日龄和17日龄孵化雏鸡的胫骨干进行常规光学显微镜检查。特征性病变是成骨细胞增生并伴有海绵骨形成。新形成的骨中含有异常软骨样组织。讨论了该实验模型中骨组织与软骨组织之间的关系。由于结缔组织参与了这种骨质增生的构成,这种骨病可被视为一种增生性、单胚层间充质、多组织性肿瘤。对有关“禽骨质增生性骨质石化症”的大量研究进行了评论。

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