Chen Minna, Wu Xiaoru, Chen Lifen, Wang Ying
Department of Nursing, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Digit Health. 2025 Sep 4;11:20552076251376261. doi: 10.1177/20552076251376261. eCollection 2025 Jan-Dec.
Digital therapeutics (DTx) has emerged as a transformative approach in healthcare, offering innovative solutions for disease management and treatment optimization. Prostate cancer (PCa), the second most common malignancy in men, has seen increasing incidence rates, driving the development of new digital technologies for PCa management.
This review aims to provide a comprehensive analysis of the current status and effectiveness of DTx in managing PCa.
Based on the framework of Arksey and O'Malley's scoping review and the PRISMA-ScR guidelines, a systematic search was conducted in major domestic and international databases. The search aimed to retrieve studies on DTx for PCa from database inception to November 2024. The retrieved data were systematically summarized and analyzed using descriptive numerical summaries and thematic content analysis.
A total of 23 studies were included. The study types were primarily randomized controlled trials. The application forms of DTx included internet-based platforms, mobile health, and wearable devices. The primary focus of DTx applications in PCa patients included survivorship support, symptom management and side-effect monitoring, psychological support and emotional management, patient education and self-management, health management and rehabilitation, and treatment adherence management.
DTx demonstrates diverse applications in the management of PCa and has shown potential in improving patients' quality of life. Future research should integrate DTx with diagnosis and therapeutic approaches, with a particular emphasis on developing DTx tools tailored explicitly for PCa patients. High-quality randomized controlled trials should be prioritized to validate these interventions further.
数字疗法(DTx)已成为医疗保健领域的一种变革性方法,为疾病管理和治疗优化提供创新解决方案。前列腺癌(PCa)是男性中第二常见的恶性肿瘤,其发病率不断上升,推动了用于PCa管理的新数字技术的发展。
本综述旨在全面分析DTx在PCa管理中的现状和有效性。
基于Arksey和O'Malley的范围综述框架以及PRISMA-ScR指南,在国内外主要数据库中进行了系统检索。检索旨在获取从数据库建立到2024年11月关于DTx用于PCa的研究。使用描述性数值摘要和主题内容分析对检索到的数据进行系统总结和分析。
共纳入23项研究。研究类型主要为随机对照试验。DTx的应用形式包括基于互联网的平台、移动健康和可穿戴设备。DTx在PCa患者中的应用主要重点包括生存支持、症状管理和副作用监测、心理支持和情绪管理、患者教育和自我管理、健康管理和康复以及治疗依从性管理。
DTx在PCa管理中显示出多种应用,并在改善患者生活质量方面显示出潜力。未来的研究应将DTx与诊断和治疗方法相结合,特别强调开发专门为PCa患者量身定制的DTx工具。应优先进行高质量的随机对照试验,以进一步验证这些干预措施。