Hjalmarsson Lydia, Bianchi Cristina, Hannabuss Joshua, Stathopoulou Thaleia
Royal Veterinary College (RVC), London, United Kingdom.
Front Vet Sci. 2025 Aug 22;12:1595738. doi: 10.3389/fvets.2025.1595738. eCollection 2025.
A retrospective analysis of dogs undergoing balloon valvuloplasty of the pulmonic valve between April 2014 and March 2023 was performed. Anaesthetic records from 44 dogs were included in the analysis. Dogs were grouped according to anaesthetic maintenance agent used, inhalational agent with partial intravenous anaesthesia (PIVA, = 31) or propofol total intravenous anaesthesia (TIVA, = 13). Variables including invasive blood pressure, heart rate, incidence of arrhythmias and requirement for interventions in the form of fluid bolus, anticholinergics and vasopressors were compared. Incidence of hypotension was significantly lower in dogs maintained on TIVA (40%) compared to PIVA (79%) ( = 0.008). Total duration of hypotension was shorter in dogs maintained on TIVA (median 40, interquartile range (IQR) 10-62.5 median 65, IQR 17.5-110 min) ( = 0.003). Systolic, mean and diastolic blood pressures were significantly higher in patients maintained on TIVA (107 ± 18, 73 ± 10 and 59 ± 8 mmHg respectively) compared to those maintained on PIVA (96 ± 15, 65 ± 9 and 52 ± 8 mmHg respectively, = 0.039, = 0.0079, = 0.0156). No significant differences in incidence of arrhythmias ( = 0.292) and heart rate (88 14 and 88 18 beats minute respectively) ( = 0.953) were seen between the two groups. There was also no significant difference in the number of interventions required to maintain normotension ( = > 0.1).
对2014年4月至2023年3月期间接受肺动脉瓣球囊成形术的犬只进行了回顾性分析。分析纳入了44只犬的麻醉记录。根据所使用的麻醉维持药物将犬只分组,吸入性药物联合部分静脉麻醉(PIVA,n = 31)或丙泊酚全静脉麻醉(TIVA,n = 13)。比较了包括有创血压、心率、心律失常发生率以及以液体冲击、抗胆碱能药物和血管升压药形式进行干预的需求等变量。与PIVA组(79%)相比,TIVA维持麻醉的犬只低血压发生率显著更低(40%)(P = 0.008)。TIVA维持麻醉的犬只低血压总持续时间更短(中位数40,四分位数间距(IQR)10 - 62.5;PIVA组中位数65,IQR 17.5 - 110分钟)(P = 0.003)。与PIVA组(分别为96±15、65±9和52±8 mmHg)相比,TIVA维持麻醉的患者收缩压、平均动脉压和舒张压显著更高(分别为107±18、73±10和59±8 mmHg,P = 0.039、P = 0.0079、P = 0.0156)。两组之间心律失常发生率(P = 0.292)和心率(分别为88±14和88±18次/分钟)(P = 0.953)无显著差异。维持血压正常所需的干预次数也无显著差异(P>0.1)。