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接受球囊瓣膜成形术治疗肺动脉狭窄的犬只的麻醉管理及麻醉并发症发生率:一项回顾性研究

Anaesthetic management and incidence of anaesthetic complications in dogs undergoing balloon valvuloplasty for treatment of pulmonic stenosis: a retrospective study.

作者信息

Hjalmarsson Lydia, Bianchi Cristina, Hannabuss Joshua, Stathopoulou Thaleia

机构信息

Royal Veterinary College (RVC), London, United Kingdom.

出版信息

Front Vet Sci. 2025 Aug 22;12:1595738. doi: 10.3389/fvets.2025.1595738. eCollection 2025.

DOI:10.3389/fvets.2025.1595738
PMID:40919028
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12411208/
Abstract

A retrospective analysis of dogs undergoing balloon valvuloplasty of the pulmonic valve between April 2014 and March 2023 was performed. Anaesthetic records from 44 dogs were included in the analysis. Dogs were grouped according to anaesthetic maintenance agent used, inhalational agent with partial intravenous anaesthesia (PIVA,  = 31) or propofol total intravenous anaesthesia (TIVA,  = 13). Variables including invasive blood pressure, heart rate, incidence of arrhythmias and requirement for interventions in the form of fluid bolus, anticholinergics and vasopressors were compared. Incidence of hypotension was significantly lower in dogs maintained on TIVA (40%) compared to PIVA (79%) ( = 0.008). Total duration of hypotension was shorter in dogs maintained on TIVA (median 40, interquartile range (IQR) 10-62.5 median 65, IQR 17.5-110 min) ( = 0.003). Systolic, mean and diastolic blood pressures were significantly higher in patients maintained on TIVA (107 ± 18, 73 ± 10 and 59 ± 8 mmHg respectively) compared to those maintained on PIVA (96 ± 15, 65 ± 9 and 52 ± 8 mmHg respectively,  = 0.039,  = 0.0079,  = 0.0156). No significant differences in incidence of arrhythmias ( = 0.292) and heart rate (88 14 and 88 18 beats minute respectively) ( = 0.953) were seen between the two groups. There was also no significant difference in the number of interventions required to maintain normotension ( = > 0.1).

摘要

对2014年4月至2023年3月期间接受肺动脉瓣球囊成形术的犬只进行了回顾性分析。分析纳入了44只犬的麻醉记录。根据所使用的麻醉维持药物将犬只分组,吸入性药物联合部分静脉麻醉(PIVA,n = 31)或丙泊酚全静脉麻醉(TIVA,n = 13)。比较了包括有创血压、心率、心律失常发生率以及以液体冲击、抗胆碱能药物和血管升压药形式进行干预的需求等变量。与PIVA组(79%)相比,TIVA维持麻醉的犬只低血压发生率显著更低(40%)(P = 0.008)。TIVA维持麻醉的犬只低血压总持续时间更短(中位数40,四分位数间距(IQR)10 - 62.5;PIVA组中位数65,IQR 17.5 - 110分钟)(P = 0.003)。与PIVA组(分别为96±15、65±9和52±8 mmHg)相比,TIVA维持麻醉的患者收缩压、平均动脉压和舒张压显著更高(分别为107±18、73±10和59±8 mmHg,P = 0.039、P = 0.0079、P = 0.0156)。两组之间心律失常发生率(P = 0.292)和心率(分别为88±14和88±18次/分钟)(P = 0.953)无显著差异。维持血压正常所需的干预次数也无显著差异(P>0.1)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bef/12411208/939b6ee52207/fvets-12-1595738-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bef/12411208/93fe7eb2c053/fvets-12-1595738-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bef/12411208/939b6ee52207/fvets-12-1595738-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bef/12411208/93fe7eb2c053/fvets-12-1595738-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bef/12411208/939b6ee52207/fvets-12-1595738-g002.jpg

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本文引用的文献

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Association between body mass and hypotension in dogs under general anaesthesia.在全身麻醉下的狗中,体重与低血压之间的关联。
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The Genetics of Canine Pulmonary Valve Stenosis.犬肺动脉瓣狭窄的遗传学研究
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Prophylactic use of a lidocaine constant rate infusion versus saline in dogs undergoing balloon valvuloplasty for management of pulmonic stenosis: A randomized control trial.
在接受球囊瓣膜成形术治疗肺动脉瓣狭窄的犬中,预防性使用利多卡因持续输注与生理盐水比较:一项随机对照试验。
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Effect of preoperative administration of atenolol to dogs with pulmonic stenosis undergoing interventional procedures.术前应用阿替洛尔对行介入治疗的肺狭窄犬的影响。
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Comparison between continuous rate infusion and target-controlled infusion of propofol in dogs: a randomized clinical trial.犬中丙泊酚持续速率输注与靶控输注的比较:一项随机临床试验。
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