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[耳鸣——当前进展:2024年当前知识状态概述与总结]

[Tinnitus-current developments : Overview and summary of current state of knowledge in 2024].

作者信息

Mazurek Birgit, Steinmetzger Kurt, Boecking Benjamin, Hesse Gerhard, Brueggemann Petra

机构信息

Tinnituszentrum, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Germany Charitéplatz 1, 10117, Berlin, Deutschland.

Tinnitus-Klinik am Krankenhaus Bad Arolsen, Große Allee 50, 34454, Bad Arolsen, Deutschland.

出版信息

HNO. 2025 Sep 8. doi: 10.1007/s00106-025-01668-3.

Abstract

Chronic tinnitus is a common symptom of the auditory system. Its pathophysiology remains incompletely understood, primarily due to its multifactorial etiology, which resembles that of other chronic conditions. As a result, effective clinical management requires interdisciplinary diagnostics and personalized therapeutic strategies. A search in PubMed using the keyword "tinnitus" covering the period from September 2023 to September 2024 yielded 1079 publications, of which the most relevant were selected and analyzed for this review summarizing current knowledge. Recent advances in tinnitus research have further refined our understanding of its pathophysiology, diagnosis, and treatment. Tinnitus is frequently triggered by cochlear damage, leading to central neuronal alterations and maladaptive plasticity. Progress in neuroimaging and psychoacoustic testing is improving diagnostic precision, while multidisciplinary treatment approaches are gaining clinical relevance and should be increasingly emphasized.

摘要

慢性耳鸣是听觉系统的常见症状。其病理生理学仍未完全被理解,主要是由于其多因素病因,这与其他慢性疾病相似。因此,有效的临床管理需要跨学科诊断和个性化治疗策略。在PubMed上使用关键词“耳鸣”进行搜索,涵盖2023年9月至2024年9月期间,共获得1079篇出版物,从中选择了最相关的文献进行分析,以总结当前知识,撰写本综述。耳鸣研究的最新进展进一步完善了我们对其病理生理学、诊断和治疗的理解。耳鸣常由耳蜗损伤引发,导致中枢神经元改变和适应性不良的可塑性。神经影像学和心理声学测试的进展正在提高诊断精度,而多学科治疗方法正获得临床相关性,应得到越来越多的重视。

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