Lira Margarida Maria Tenório de Azevedo, de Freitas Marina, Bonilha Eliana de Aquino, Aly Célia Maria Castex, Dos Santos Patrícia Carla, Niy Denise Yoshie, Diniz Carmen Simone Grilo
Potential Pregnancy Days Lost Study, São Paulo, Brazil.
São Camilo University Center, São Paulo, Brazil.
PLoS One. 2025 Sep 8;20(9):e0319307. doi: 10.1371/journal.pone.0319307. eCollection 2025.
Studies have shown that excessive obstetric interventions such as induced labor and caesarean sections have contributed to the shortening of the length of gestation, leading to a left shift in gestational age (GA) at birth. The aim of this study was to analyze trends in GA and the contribution of associated factors to changes in São Paulo city, Brazil during the period 2012-2019. We conducted an observational time-series study of births in São Paulo using data from Brazil's national live births information system (SINASC). We calculated the annual percent change (APC) of births by GA between 2012 and 2019 and between the first and second four-year periods of the time series by applying log transformation to the percentages, followed by Prais-Winsten regression. A total of 1,525,759 live births were analyzed. From 2015, there was an increase in the proportion of live births between 39 and 40 weeks from 2015 and a fall in the proportion of early term (37-38 weeks) and preterm (< 37 weeks) births throughout the study period. The APC of births at 39 and 40 weeks was 7.9% and 5.7%, respectively, while the proportion of births at other gestational ages showed a statistically significant reduction over the study period. These reductions were more pronounced in the first four-year period (2012-2015). The same trend was observed when the data were analyzed by type of delivery, type of service (public or private), maternal age, and maternal education level. The findings show that there was a right shift in the GA curve during the study period and a reduction in the proportion of preterm and early term births. These changes were more pronounced in births that occurred in private hospitals. These changes reflect public policies implemented to reduce obstetric interventions such as induced labor and caesarean section before labor, especially before 39 weeks of gestation.
研究表明,引产和剖宫产等过度的产科干预导致了妊娠期缩短,致使出生时孕周(GA)左移。本研究的目的是分析2012 - 2019年期间巴西圣保罗市孕周的变化趋势以及相关因素对变化的影响。我们利用巴西国家活产信息系统(SINASC)的数据,对圣保罗市的出生情况进行了一项观察性时间序列研究。通过对百分比进行对数变换,然后进行普雷斯 - 温斯顿回归,我们计算了2012年至2019年以及时间序列的前四年和后四年期间按孕周划分的出生年百分比变化(APC)。共分析了1,525,759例活产。从2015年起,39至40周活产的比例增加,且在整个研究期间,早期足月(37 - 38周)和早产(< 37周)出生的比例下降。39周和40周出生的APC分别为7.9%和5.7%,而其他孕周出生的比例在研究期间呈现出统计学上的显著下降。这些下降在第一个四年期(2012 - 2015年)更为明显。按分娩类型、服务类型(公立或私立)、产妇年龄和产妇教育水平分析数据时,观察到了相同的趋势。研究结果表明,在研究期间GA曲线出现了右移,早产和早期足月出生的比例降低。这些变化在私立医院出生的情况中更为明显。这些变化反映了为减少引产和临产前剖宫产等产科干预措施而实施的公共政策,尤其是在妊娠39周之前。